Announcing OMF's First ME/CFS Clinical Trial!

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Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS) Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia Leading Research. Delivering Hope.Open Medicine Foundation® Canada

Driving research of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS),
Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia and Long COVID.

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Category: News

LAST CHANCE to TRIPLE your gift in 2023! Support a future of clinical trials!

Researcher working with lab specimens.

Today, November 30, 2023, marks the LAST DAY of our Triple Giving November campaign and the future has never looked brighter! The path forward is paved with clinical trials aimed at finding the most effective treatments fast. However, the success of these clinical trials hinges on the collective support from individuals like you.   Don’t miss […]

TRIPLE your gift & change lives like Ashanti’s – Act Before Match Runs Out!

Woman in pink dress

“I was living my best life…It was like being hit by a train I never saw coming.” Ashanti’s words show the reality faced by those battling ME/CFS and Long COVID daily. Her journey from being a vibrant NICU nurse, enjoying life in her 30s, to fighting an unseen, unheard enemy, is more than a story. It’s […]

Exclusive! Dr. Jonas Bergquist Discusses OMF’s First Clinical Trial

Jonas Bergquist in a white lab coat

  We invite you for an exclusive conversation with Jonas Bergquist, MD, Ph.D., OMF’s Chief Medical Officer and Director of the Uppsala University Collaboration. Today, Dr. Bergquist sheds light on The LifeImprovement Trial (LIFT), responding to key questions.  As a reminder, only THREE days remain in Triple Giving November, where every donation to OpenMedicine Foundation (OMF) is TRIPLED, […]

Don’t miss out! 3X the impact on research

“I once chased the perfect wave. Now, I chase the hope for a cure.”    Robert had to stop his passion of surfing, traveling, and working towards a promising business career because of ME/CFS. He says, “When I wasn’t surfing, I was working towards a business career and had three great job offers.” He even […]

Publications from Research Funded by Open Medicine Foundation

We are excited to share a comprehensive overview of the publications that have resulted from research funded by Open Medicine Foundation. Our dedicated team of researchers and collaborators has been at the forefront of uncovering the complexities of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). This eblast will guide you through the various categories of our publications, […]

Dr. Lucinda Bateman Joins OMF Scientific Advisory Board

  Open Medicine Foundation (OMF) is thrilled to announce that Dr. Lucinda Bateman has joined our esteemed Scientific Advisory Board. Her appointment serves as a testament to our ongoing commitment to fostering a multidisciplinary approach to medical research and care, ensuring we remain at the forefront of innovative research. Dr. Bateman’s dedication to patient care, […]

Meet Sammy Lincroft: Advocate for ME/CFS and OMF Supporter!

mobility and ME/CFS

As part of this year’s Triple Giving November campaign, we are honored to introduce Sammy Lincroft, a dedicated advocate for chronic illnesses. Sammy is a strong supporter of Open Medicine Foundation in alignment with her advocacy for ME/CFS and disability justice. She runs a blog, www.meandmore.net, and an Instagram account, @m.e_and_more, where she provides valuable […]

Dr. David Systrom Discusses OMF’s LIFT Clinical Trial

David Systrom

Today Dr. David Systrom sits down to chat about OMF’s first clinical trial, The Life Improvement Trial (LIFT). What is The LIFT? Conducted under the direction of David Systrom, MD, Director of OMF’s Harvard Collaboration and Jonas Bergquist, MD, PhD, OMF’s Chief Medical Officer and Director of the Uppsala University Collaboration, The LIFT is a […]

How does OMF Choose Treatments for Clinical Trials? A Transparent Look

OMF Directors at Annual Gathering 2023

Our recent Research Directors Meeting this October was a testament to our commitment to collaborative discussions. As all the research directors gathered in person, a major part of the agenda was to discuss the methodology behind choosing treatments for clinical trials. We are excited to now share this process with you.  Last week, you may have […]

News! OMF’s First Clinical Trial!

We are thrilled to announce our very first clinical trial: The Life Improvement Trial (LIFT). This clinical treatment trial is a major step towards understanding and treating Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) more effectively. What is The LIFT? Conducted under the direction of David Systrom, MD, Director of our Harvard Collaboration and Jonas Bergquist, MD, […]

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Microvesicles and viral sequencing
Microvesicles are a type of extracellular vesicle that is released from the cell membrane. Vesicles are small, fluid-filled sacs or vacuoles within the body. Sequencing is a technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA (or viral) molecule.
NMR Metabolomics
NMR (Nuclear Magnetic Resonance) is an instrument/tool used to perform metabolic studies, metabolic profiling, and metabolomics in biofluids and tissues for more than 40 years using magnetic fields. There is a very close connection between metabolic measurements and NMR. This connection has flourished because of NMR’s many unique strengths for characterizing complex mixtures’ chemical composition.
Proteomics
The large-scale study of proteins, which are large, complex molecules that are required for structure, function, and regulation of the human body's tissues and organs.
Immune cell profiling
The immune system has many important regulatory roles in disease development and progression. Given the emergence of effective immune therapies, reliable predictors of response are needed. Immune cell profiling determines response by evaluating immune cell populations from treated and untreated samples. For our purposes, we will evaluate the white blood cell response to the viral infection using a process called “Cytof.”
Leukocyte Genomics
A leukocyte is a colorless cell circulating in the blood and body fluids and is involved in counteracting foreign substances and disease. A genome is all genetic material of an organism. Genomics is a biology field focusing on the structure, function, evolution, mapping, and editing of genomes. Therefore, leukocyte genomics is the study of all genetic material of leukocytes.
Metabolomics
Metabolomics is a way to study metabolism – that is, through measuring amounts of the metabolites (small molecules) produced by our bodies as we convert food into energy and other molecules that our cells need to survive. Metabolomics technology is ‘large-scale,’ meaning that several thousand metabolites can be measured from a single sample of e.g., blood or urine.
Micro RNA
Cells use Micro RNA to control whether a particular gene is making too much, too little or the normal amount of its protein at a particular time.
Autoantibodies
Antibodies that react with self-molecules and that occur in healthy individuals and are referred to as natural antibodies or autoantibodies.
Extracellular DNA for viral reactivation and Mitochondrial DNA
exDNA (extracellular DNA), exDNA is often secreted actively and is used to perform several tasks, thereby offering an attractive target or tool for biotechnological, medical, environmental, and general microbiological applications. Viruses are intracellular parasites that rely to a significant extent on the host cell for replication. Viral reactivation occurs when an active replication of the viral genome results in a lytic (degradation of the cell) infection characterized by the release of new progeny (descendant) virus particles.