Announcing OMF's First ME/CFS Clinical Trial!

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Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS) Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia Leading Research. Delivering Hope.Open Medicine Foundation® Canada

Driving research of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS),
Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia and Long COVID.

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Support The End ME/CFS Project!

Do you count yourself as one of the over 800 members of the international ME/CFS community that are part of Open Medicine Foundation’s 2020 #MayMomentum? If so, we could not be more grateful! If you are still waiting to give, there are just four days left to join your community and our annual #MayMomentum campaign […]

OMF Announces New Treatment Trial

As part of #MayMomentum, Open Medicine Foundation is thrilled to announce a new clinical trial that builds on OMF funded research and shows the interconnected strategies of the four OMF Funded ME / CFS Collaborative Research Centers. We hope that you will agree that this thoughtful research strategy deserves your support and that today is the day that […]

A Powerful Message from Whitney Dafoe

We are honored to share an excerpt from a message from Whitney Dafoe… “My name is Whitney Dafoe and I have severe Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS). I have had symptoms for 15 years but have slowly gotten worse because of a lack of beneficial treatments. I am only able to communicate by taking a […]

Breaking News – OMF Funded Study: COVID-19 and ME/CFS

Breaking News OMF Funded Study: COVID-19 and ME/CFS   Against the backdrop of COVID-19, Open Medicine Foundation (OMF) remains focused on finding the answers needed to win the fight against Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS) and other chronic, complex diseases. Today, because of the pandemic, an opportunity exists to increase the understanding of ME/CFS. OMF is […]

International Awareness Day 2020

Today, OMF is continuing our momentum as we honor International Awareness Day for Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS) & Fibromyalgia (FM). We have invited our Social Media Coordinator, Rebecca Handler, to share, in her own words and images, why today means so much to all of us: Today, May 12th, 2020, marks International Awareness Day […]

OMF Funds ME/CFS Treatment Trial

  As someone aware of the impact of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS), you understand, as we do, that there is an urgent need to improve the clinical care for people suffering from this devastating condition. #MayMomentum is all about ensuring that research into ME/CFS and other related chronic, complex diseases leads to results and to […]

Study of the possible conversion of COVID-19 patients to ME / CFS

COVID-19 illustration

Open Medicine Foundation is excited to announce the initiation of a study of patients with COVID-19 to monitor the course of their disease and its sequelae to ascertain whether they convert to Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS) and to study the molecular transformation if it occurs. This will involve  collection of body fluid samples at […]

Kynurenine Clinical Trial for ME / CFS

Open Medicine Foundation is excited to announce its support of an initiation of a clinical trial to understand potential disturbances in the tryptophan metabolism and to test the benefits of treating people with Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS) with Kynurenine. Kynurenine is naturally produced in the body, is a key metabolite in the tryptophan metabolism, […]

OMF Adds a Fourth ME / CFS Collaborative Research Center

BREAKING NEWS We are pleased to announce that we have added a fourth ME / CFS Collaborative Research Center (CRC) to join our End ME / CFS Project. Directed by Alain Moreau, PhD, the ME / CFS Collaborative Research Center at CHU Sainte-Justine/Université de Montréal in Québec, Canada will serve to increase our international collaborative efforts. Dr. Moreau and his lab have […]

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Microvesicles and viral sequencing
Microvesicles are a type of extracellular vesicle that is released from the cell membrane. Vesicles are small, fluid-filled sacs or vacuoles within the body. Sequencing is a technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA (or viral) molecule.
NMR Metabolomics
NMR (Nuclear Magnetic Resonance) is an instrument/tool used to perform metabolic studies, metabolic profiling, and metabolomics in biofluids and tissues for more than 40 years using magnetic fields. There is a very close connection between metabolic measurements and NMR. This connection has flourished because of NMR’s many unique strengths for characterizing complex mixtures’ chemical composition.
Proteomics
The large-scale study of proteins, which are large, complex molecules that are required for structure, function, and regulation of the human body's tissues and organs.
Immune cell profiling
The immune system has many important regulatory roles in disease development and progression. Given the emergence of effective immune therapies, reliable predictors of response are needed. Immune cell profiling determines response by evaluating immune cell populations from treated and untreated samples. For our purposes, we will evaluate the white blood cell response to the viral infection using a process called “Cytof.”
Leukocyte Genomics
A leukocyte is a colorless cell circulating in the blood and body fluids and is involved in counteracting foreign substances and disease. A genome is all genetic material of an organism. Genomics is a biology field focusing on the structure, function, evolution, mapping, and editing of genomes. Therefore, leukocyte genomics is the study of all genetic material of leukocytes.
Metabolomics
Metabolomics is a way to study metabolism – that is, through measuring amounts of the metabolites (small molecules) produced by our bodies as we convert food into energy and other molecules that our cells need to survive. Metabolomics technology is ‘large-scale,’ meaning that several thousand metabolites can be measured from a single sample of e.g., blood or urine.
Micro RNA
Cells use Micro RNA to control whether a particular gene is making too much, too little or the normal amount of its protein at a particular time.
Autoantibodies
Antibodies that react with self-molecules and that occur in healthy individuals and are referred to as natural antibodies or autoantibodies.
Extracellular DNA for viral reactivation and Mitochondrial DNA
exDNA (extracellular DNA), exDNA is often secreted actively and is used to perform several tasks, thereby offering an attractive target or tool for biotechnological, medical, environmental, and general microbiological applications. Viruses are intracellular parasites that rely to a significant extent on the host cell for replication. Viral reactivation occurs when an active replication of the viral genome results in a lytic (degradation of the cell) infection characterized by the release of new progeny (descendant) virus particles.