This software would rapidly identify disease or symptom exacerbators that may be due to genetic mutation of environmental stressors in individuals with ME/CFS. This will provide a better understanding of the symptom expression in ME/CFS and help identify secondary issues or chronic triggers that are exacerbating/maintaining the disease.
Identifying these issues or stressors will enable them to be more accurately treated and improve quality of life in people with ME/CFS
PROTOCOL DESCRIPTION
The software developed would use machine learning to identify outlier anomalies that are consistent across genomics, proteomics, and metabolomics data from an individual. A report would be produced to highlight the probability of genetic mutations relating to a functional effect.
PROTOCOL DEVELOPMENT
The data required to develop this software will be immense and will consist of many previously produced datasets from our collaborators. A significant amount of priming and testing of this software will occur through the accumulation of genomics, metabolomics and symptom data from 300 ME / CFS patients.
Gene mutations, metabolite levels and symptom data will be analyzed to identify outlier metabolites and metabolites that relates strongly to symptom data. Genetic mutations and environmental factors will be considered causes of these outliers by machine-learning technology.
Software will be developed specifically to store patterns developed from patient data and more rapidly check those patterns against new patient data to rapidly identify potential issues that may be exacerbating or triggering symptoms in people with ME / CFS.
Donate your appreciated stock directly to OMFCA and you can receive an immediate income-tax deduction for the fair market value of the securities on the date of transfer (even if you originally paid much less for them).
OMFCA sells your securities and uses the proceeds to support our mission. You also do not pay capital gains tax on the transfer when the stock is sold. Giving appreciated stock can be more beneficial than giving cash. The “cost” of your gift is often less than the deduction you gain by making it. In advance, thank you for making this generous gift.
Gifting of Stock Instructions
Brokerage/Investment Firm: TD Waterhouse
Name on the Account: Open Medicine Foundation Canada
Account Number: 20LRHLA
OMFCA Canadian Revenue Agency (CRA) charity registration #: 74926 5518 RR0001
OMF Canada Registered Address:
Open Medicine Foundation Canada
2987 Baynes Road, Victoria, BC V8N-1Y4
Phone Number: 416-848-0055
Please speak to your personal tax advisor and then call OMFCA at 650-242-8669 to notify us of your donation or with any questions.