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Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS) Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia Leading Research. Delivering Hope.Open Medicine Foundation® Canada
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Join Daniel in Bringing Hope to ME/CFS Research: Become a Hope Builder Today!

This month, we are challenging ourselves to welcome 30 new monthly donors—our dedicated “Hope Builders.” Join other supporters in making a lasting impact by becoming a Hope Builder today. 

The image shows Daniel smiling warmly at the camera. He is wearing glasses and a black jacket over a light gray shirt.“Six years ago, I was working as a Software Engineer and writer, feeling healthier than I had in years — until I suddenly became ill with ME/CFS. Over time, my symptoms worsened, forcing me to leave my job and rethink what parts of my life I could still hold onto. Living with ME/CFS can make hope hard to find, but knowing that Open Medicine Foundation is working hard to understand this disease gives me real optimism.

 

That’s why I’m proud to be a Hope Builder, supporting OMF’s work every month. Monthly gifts, of any amount, provide steady funding to accelerate research and move us closer to treatments and a cure. If you’re able, I encourage you to join me — together, we can help create a brighter future for everyone living with ME/CFS.”

 

~ Daniel

Become a Hope Builder

Daniel is one of our dedicated Hope Builders. His story is a poignant reminder of why we must persist in our fight against ME/CFS and Long COVID. 

 

Help us reach our goal to welcome 30 new Hope Builders by the end of March. Your monthly or one-time donation can make a real difference in accelerating research and bringing hope to those affected by these debilitating diseases.

Already a monthly donor? Thank you for your incredible support! Please consider sharing this email with friends and family to help us reach our goal.

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Microvesicles and viral sequencing
Microvesicles are a type of extracellular vesicle that is released from the cell membrane. Vesicles are small, fluid-filled sacs or vacuoles within the body. Sequencing is a technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA (or viral) molecule.
NMR Metabolomics
NMR (Nuclear Magnetic Resonance) is an instrument/tool used to perform metabolic studies, metabolic profiling, and metabolomics in biofluids and tissues for more than 40 years using magnetic fields. There is a very close connection between metabolic measurements and NMR. This connection has flourished because of NMR’s many unique strengths for characterizing complex mixtures’ chemical composition.
Proteomics
The large-scale study of proteins, which are large, complex molecules that are required for structure, function, and regulation of the human body's tissues and organs.
Autoantibodies
Antibodies that react with self-molecules and that occur in healthy individuals and are referred to as natural antibodies or autoantibodies.
Extracellular DNA for viral reactivation and Mitochondrial DNA
exDNA (extracellular DNA), exDNA is often secreted actively and is used to perform several tasks, thereby offering an attractive target or tool for biotechnological, medical, environmental, and general microbiological applications. Viruses are intracellular parasites that rely to a significant extent on the host cell for replication. Viral reactivation occurs when an active replication of the viral genome results in a lytic (degradation of the cell) infection characterized by the release of new progeny (descendant) virus particles.
Immune cell profiling
The immune system has many important regulatory roles in disease development and progression. Given the emergence of effective immune therapies, reliable predictors of response are needed. Immune cell profiling determines response by evaluating immune cell populations from treated and untreated samples. For our purposes, we will evaluate the white blood cell response to the viral infection using a process called “Cytof.”
Leukocyte Genomics
A leukocyte is a colorless cell circulating in the blood and body fluids and is involved in counteracting foreign substances and disease. A genome is all genetic material of an organism. Genomics is a biology field focusing on the structure, function, evolution, mapping, and editing of genomes. Therefore, leukocyte genomics is the study of all genetic material of leukocytes.
Metabolomics
Metabolomics is a way to study metabolism – that is, through measuring amounts of the metabolites (small molecules) produced by our bodies as we convert food into energy and other molecules that our cells need to survive. Metabolomics technology is ‘large-scale,’ meaning that several thousand metabolites can be measured from a single sample of e.g., blood or urine.
Micro RNA
Cells use Micro RNA to control whether a particular gene is making too much, too little or the normal amount of its protein at a particular time.