Driving research of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS),
Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia and Post COVID .

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NEW interview with Karin Alvtegen, OMF Ambassador & bestselling author!

#TripleGivingTuesday Ambassador Spotlight: NEW interview with Karin Alvtegen, OMF Ambassador & bestselling author! OMF Ambassador Karin Alvtegen is celebrated as one of Scandinavia’s most widely …

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We’re increasing our #TripleGivingTuesday goal!

We’re increasing our Triple Giving Tuesday goal! OMF is thrilled to announce two additional anonymous matching gift donors have stepped up with matching gifts totaling …

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OMF funds new treatment-focused project

#TripleGivingTuesday Research Update: OMF Funds New Treatment-Focused Project From the desk of Ronald Tompkins, MD, ScDChief Medical Officer, Open Medicine Foundation About the Project As …

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Influencer Rea Strawhill talks chronic illness advocacy online!

Creating safe space for people with chronic illness on social media: An interview with advocate & person with ME: Rea Strawhill As part of this …

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OMF Awarded 2nd Score of 100 on Charity Navigator!

OMF Awarded Score of 100 on Charity Navigator! OMF is proud to share that we have received our second score of “100 Encompass Rating” in the Leadership …

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Three new groundbreaking research projects!

#TripleGivingTuesday Research Feature A conversation with Dr. Alain Moreau: Three groundbreaking research projects underway! 🔬 It’s the third week of #TripleGivingTuesday, OMF’s largest fundraising campaign …

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Supporting disabled artists: Exclusive interview with Jacqueline Ko!

#TripleGivingTuesday Ambassador Spotlight How Jacqueline Ko is “Holding Space” for artists with disabilities and chronic illnesses Multi-award-winning opera singer and Canadian OMF Ambassador Jacqueline Ko, …

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New Study Alert! Sleep Disturbances in ME/CFS

#TripleGivingTuesday news: New Study Underway! Sleep Disturbances in ME/CFS From the desk of Ronald Tompkins, MD, ScDDirector, ME/CFS Harvard CollaborationChief Medical Officer, Open Medicine Foundation …

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New study underway at the Montreal Collaborative Center!

#TripleGivingTuesday Research Feature New OMF funded study: Deep proteome and metabolome profiling From the desk of Alain Moreau, PhDDirector of the ME/CFS Collaborative Research Center …

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Microvesicles and viral sequencing
Microvesicles are a type of extracellular vesicle that is released from the cell membrane. Vesicles are small, fluid-filled sacs or vacuoles within the body. Sequencing is a technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA (or viral) molecule.
NMR Metabolomics
NMR (Nuclear Magnetic Resonance) is an instrument/tool used to perform metabolic studies, metabolic profiling, and metabolomics in biofluids and tissues for more than 40 years using magnetic fields. There is a very close connection between metabolic measurements and NMR. This connection has flourished because of NMR’s many unique strengths for characterizing complex mixtures’ chemical composition.
Proteomics
The large-scale study of proteins, which are large, complex molecules that are required for structure, function, and regulation of the human body's tissues and organs.
Immune cell profiling
The immune system has many important regulatory roles in disease development and progression. Given the emergence of effective immune therapies, reliable predictors of response are needed. Immune cell profiling determines response by evaluating immune cell populations from treated and untreated samples. For our purposes, we will evaluate the white blood cell response to the viral infection using a process called “Cytof.”
Leukocyte Genomics
A leukocyte is a colorless cell circulating in the blood and body fluids and is involved in counteracting foreign substances and disease. A genome is all genetic material of an organism. Genomics is a biology field focusing on the structure, function, evolution, mapping, and editing of genomes. Therefore, leukocyte genomics is the study of all genetic material of leukocytes.
Metabolomics
Metabolomics is a way to study metabolism – that is, through measuring amounts of the metabolites (small molecules) produced by our bodies as we convert food into energy and other molecules that our cells need to survive. Metabolomics technology is ‘large-scale,’ meaning that several thousand metabolites can be measured from a single sample of e.g., blood or urine.
Micro RNA
Cells use Micro RNA to control whether a particular gene is making too much, too little or the normal amount of its protein at a particular time.
Autoantibodies
Antibodies that react with self-molecules and that occur in healthy individuals and are referred to as natural antibodies or autoantibodies.
Extracellular DNA for viral reactivation and Mitochondrial DNA
exDNA (extracellular DNA), exDNA is often secreted actively and is used to perform several tasks, thereby offering an attractive target or tool for biotechnological, medical, environmental, and general microbiological applications. Viruses are intracellular parasites that rely to a significant extent on the host cell for replication. Viral reactivation occurs when an active replication of the viral genome results in a lytic (degradation of the cell) infection characterized by the release of new progeny (descendant) virus particles.