Driving research of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS),
Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia and Post COVID .

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20 reasons to give the gift of hope this year!

Last chance to donate in 2020! As we come to the end of 2020, Open Medicine Foundation Canada (OMFCA) wishes you and yours a peaceful …

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Run Across Ontario | An OMFCA Supporter’s Journey to Raise Awareness

Today we are honored to share the incredible story of Open Medicine Foundation Canada (OMFCA) supporter Terry from Canada, who has embarked on a challenging …

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Meet Dr. Rosa Maria Pari Ñaña, Award Winning ME/CFS Researcher

From the desk of Ronald Tompkins, MD, ScD Chief Medical Officer, Open Medicine Foundation An Interview with ME/CFS ResearcherDr. Rosa Maria Pari Ñaña In case you …

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Meet Dr. Dan Wilkinson, Award Winning ME/CFS Researcher

From the desk of Ronald Tompkins, MD, ScD Chief Medical Officer, Open Medicine Foundation ME/CFS researchers receive prestigious award for innovative studies I am pleased …

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Giving Thanks for You | #TripleGivingTuesdayOMF

Giving Thanks for You #TripleGivingTuesdayOMF Through the generosity of our supporters worldwide, Open Medicine Foundation (OMF) is pleased to share that we raised over $1,324,747 million …

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Last Chance to Triple Your Impact! | #TripleGivingTuesdayOMF

Last Chance to Triple Your Impact! #GivingTuesday Today, December 1, 2020, is the LAST chance for you to donate to Open Medicine Foundation Canada and …

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Last Day to Triple Your Investment in ME/CFS Research | #TripleGivingTuesdayOMF

Last Day to Triple Your Investmentin ME/CFS Research Thanks to the generosity of our supporters worldwide, we have surpassed our original fundraising goal for Triple …

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Make 6x the Impact Through Facebook Matching Gift | #TripleGivingTuesdayOMF

Make 6x the Impact Through Facebook Matching Gift We have a unique opportunity to share with you: Donate to OMF’s Facebook Fundraiser on Tuesday, Dec. …

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Transforming Diagnosis and Treatment of Chronic Complex Diseases | #TripleGivingTuesday

From the desk of Ronald Tompkins, MD, ScD Chief Medical Officer, Open Medicine Foundation #TripleGivingTuesday Research News Transforming the Diagnosis and Treatment of ME/CFS, Post-Treatment …

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NMR Metabolomics
NMR (Nuclear Magnetic Resonance) is an instrument/tool used to perform metabolic studies, metabolic profiling, and metabolomics in biofluids and tissues for more than 40 years using magnetic fields. There is a very close connection between metabolic measurements and NMR. This connection has flourished because of NMR’s many unique strengths for characterizing complex mixtures’ chemical composition.
Proteomics
The large-scale study of proteins, which are large, complex molecules that are required for structure, function, and regulation of the human body's tissues and organs.
Microvesicles and viral sequencing
Microvesicles are a type of extracellular vesicle that is released from the cell membrane. Vesicles are small, fluid-filled sacs or vacuoles within the body. Sequencing is a technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA (or viral) molecule.
Micro RNA
Cells use Micro RNA to control whether a particular gene is making too much, too little or the normal amount of its protein at a particular time.
Autoantibodies
Antibodies that react with self-molecules and that occur in healthy individuals and are referred to as natural antibodies or autoantibodies.
Extracellular DNA for viral reactivation and Mitochondrial DNA
exDNA (extracellular DNA), exDNA is often secreted actively and is used to perform several tasks, thereby offering an attractive target or tool for biotechnological, medical, environmental, and general microbiological applications. Viruses are intracellular parasites that rely to a significant extent on the host cell for replication. Viral reactivation occurs when an active replication of the viral genome results in a lytic (degradation of the cell) infection characterized by the release of new progeny (descendant) virus particles.
Immune cell profiling
The immune system has many important regulatory roles in disease development and progression. Given the emergence of effective immune therapies, reliable predictors of response are needed. Immune cell profiling determines response by evaluating immune cell populations from treated and untreated samples. For our purposes, we will evaluate the white blood cell response to the viral infection using a process called “Cytof.”
Leukocyte Genomics
A leukocyte is a colorless cell circulating in the blood and body fluids and is involved in counteracting foreign substances and disease. A genome is all genetic material of an organism. Genomics is a biology field focusing on the structure, function, evolution, mapping, and editing of genomes. Therefore, leukocyte genomics is the study of all genetic material of leukocytes.
Metabolomics
Metabolomics is a way to study metabolism – that is, through measuring amounts of the metabolites (small molecules) produced by our bodies as we convert food into energy and other molecules that our cells need to survive. Metabolomics technology is ‘large-scale,’ meaning that several thousand metabolites can be measured from a single sample of e.g., blood or urine.