Announcing OMF's First ME/CFS Clinical Trial!

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Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS) Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia Leading Research. Delivering Hope.Open Medicine Foundation® Canada

Driving research of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS),
Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia and Long COVID.

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Person Role: Foundation Board Members

Brent Handle

Brent Handel​, headshot

Brent Handel has been a lawyer for over 30 years and practices in the area of Civil Litigation and Insurance Law.  He was appointed a Queen’s Counsel (Q.C.) on December 30, 2011. This honorary title is intended to recognize a lawyer’s achievement and standing in the legal profession for quality work, professional integrity, and outstanding […]

Kathryn Bach

Katie has spent her career in a range of strategy and leadership roles in both the for-profit and non-profit sector. She is currently the Managing Director of the Good Jobs Institute, a non-profit dedicated to helping companies thrive by creating good jobs. Prior to joining the Good Jobs Institute, Katie was a Director of Global […]

Carol E. Jensen

Carol is currently the Chief People Officer and Senior Vice President of Flatiron Health, Inc., a technology company that has built a platform to enable actionable insights to improve treatment options and accelerate research for cancer patients.  Carol has overall responsibility for the people team function (including Total Rewards, Leadership Development, Human Resources Business Partners, […]

Hany Zayed, PhD

Hany Zayed, Ph.D. is the head of Data Science Solutions group at Rigel Pharmaceuticals. He has more than 25 years’ experience in statistical analysis and consulting including design of clinical studies, data analysis and results interpretation. Hany has extensive experience in strategic clinical research including due diligence evaluations, post-approval clinical trials and disease/product registries. His […]

Deborah Rose, MD

Dr. Rose is a psychiatrist in private practice in Palo Alto, California. She has over 40 years of experience in treating posttraumatic stress disorder, both acute PTSD and complex PTSD. She has developed and published a model for psychodynamic psychotherapy of PTSD and has published articles and book chapters on these subjects. She has taught […]

Joseph Morin

Joseph Morin is Co-Founder / CEO Social Rewards – a Social Media based marketing platform. Prior to founding Social Rewards, Joseph served as Vice President of Search and Social Marketing for Fly.com (a Travelzoo (NASDAQ:TZOO) company) and also served as Vice President of Strategic Marketing for UsedCars.com where as a Principal, he was instrumental in […]

Patti Linsley, Secretary

Ms. Linsley is a senior vice president of Crescent Capital Group LP. She is responsible for directing Crescent’s charitable giving activities. She is also responsible for coordinating Crescent’s annual Partners Conference. Before taking this role in the company, she managed the Human Resources department for 24 years. Prior to joining the Crescent team, Ms. Linsley […]

Kimberly Hicks, Treasurer

As a Partner and Co-Founder of KMT Partners, and CEO of her own firm, Ms. Hicks provides consulting and advisory services to boards, investors, and management teams on building value and sustainability for profit and non-profit organizations and is currently focused on projects in the healthcare industry. Having recently served as Chief Administrative Officer of […]

Linda Tannenbaum, Founder & CEO/President

The inception of Open Medicine Foundation (OMF) traces back to the personal journey of its founder, Linda Tannenbaum. As OMF’s President and CEO, Linda’s motivation was deeply personal; her daughter, at the age of 16, was struck by ME/CFS, a diagnosis that came without the prospect of diagnostic tests or viable treatments. Confronted with the painful reality of […]

Linda Tannenbaum, Fondatrice & Présidente- Directrice Générale

Linda Tannenbaum est fondatrice et présidente-directrice générale de l’Open Medicine Foundation (OMF), un organisme indépendant à but non lucratif voué au financement et à la facilitation de la recherche scientifique ouverte et collaborative en vue de faire des percées cliniques pour les maladies chroniques complexes, comme l’encéphalomyélite myalgique/le syndrome de fatigue chronique (EM/SFC). Mme Tannenbaum […]

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Microvesicles and viral sequencing
Microvesicles are a type of extracellular vesicle that is released from the cell membrane. Vesicles are small, fluid-filled sacs or vacuoles within the body. Sequencing is a technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA (or viral) molecule.
NMR Metabolomics
NMR (Nuclear Magnetic Resonance) is an instrument/tool used to perform metabolic studies, metabolic profiling, and metabolomics in biofluids and tissues for more than 40 years using magnetic fields. There is a very close connection between metabolic measurements and NMR. This connection has flourished because of NMR’s many unique strengths for characterizing complex mixtures’ chemical composition.
Proteomics
The large-scale study of proteins, which are large, complex molecules that are required for structure, function, and regulation of the human body's tissues and organs.
Immune cell profiling
The immune system has many important regulatory roles in disease development and progression. Given the emergence of effective immune therapies, reliable predictors of response are needed. Immune cell profiling determines response by evaluating immune cell populations from treated and untreated samples. For our purposes, we will evaluate the white blood cell response to the viral infection using a process called “Cytof.”
Leukocyte Genomics
A leukocyte is a colorless cell circulating in the blood and body fluids and is involved in counteracting foreign substances and disease. A genome is all genetic material of an organism. Genomics is a biology field focusing on the structure, function, evolution, mapping, and editing of genomes. Therefore, leukocyte genomics is the study of all genetic material of leukocytes.
Metabolomics
Metabolomics is a way to study metabolism – that is, through measuring amounts of the metabolites (small molecules) produced by our bodies as we convert food into energy and other molecules that our cells need to survive. Metabolomics technology is ‘large-scale,’ meaning that several thousand metabolites can be measured from a single sample of e.g., blood or urine.
Micro RNA
Cells use Micro RNA to control whether a particular gene is making too much, too little or the normal amount of its protein at a particular time.
Autoantibodies
Antibodies that react with self-molecules and that occur in healthy individuals and are referred to as natural antibodies or autoantibodies.
Extracellular DNA for viral reactivation and Mitochondrial DNA
exDNA (extracellular DNA), exDNA is often secreted actively and is used to perform several tasks, thereby offering an attractive target or tool for biotechnological, medical, environmental, and general microbiological applications. Viruses are intracellular parasites that rely to a significant extent on the host cell for replication. Viral reactivation occurs when an active replication of the viral genome results in a lytic (degradation of the cell) infection characterized by the release of new progeny (descendant) virus particles.