Announcing OMF's First ME/CFS Clinical Trial!

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Driving research of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS),
Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia and Long COVID.

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Recording Available for Webinar by OMF Canada

If you couldn’t join Open Medicine Foundation Canada (OMFCA) last Saturday, October 3, for our presentation on OMFCA-funded ME/CFS research, don’t worry — you can watch the recording on YouTube! We hope you enjoy learning about our current research initiatives and strategic partners from our founder & CEO/President, Linda Tannenbaum, and science liaison, Chris Armstrong.

Click below to watch our recording of the  presentation and download the slides for your reference.

Download the slides

If you believe in our mission and are passionate about finding a cure for ME/CFS, we encourage you to join us in raising awareness of the disease during our upcoming Triple Giving Tuesday campaign! Starting October 20, any donation made to OMFCA through December 1 will be tripled thanks to some generous donors. That’s triple the impact into critical research of ME/CFS!

Stay tuned for some exciting research updates coming soon, and keep your eyes peeled for ways to get involved in #TripleGivingTuesdayOMF!

If you are able, please consider contributing to our effort to 
uncover research-based answers.

Help us improve the quality of life for all sufferers of ME/CFS and other 
chronic complex diseases, such as Post Treatment Lyme Disease Syndrome 
and Fibromyalgia. 

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Microvesicles and viral sequencing
Microvesicles are a type of extracellular vesicle that is released from the cell membrane. Vesicles are small, fluid-filled sacs or vacuoles within the body. Sequencing is a technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA (or viral) molecule.
NMR Metabolomics
NMR (Nuclear Magnetic Resonance) is an instrument/tool used to perform metabolic studies, metabolic profiling, and metabolomics in biofluids and tissues for more than 40 years using magnetic fields. There is a very close connection between metabolic measurements and NMR. This connection has flourished because of NMR’s many unique strengths for characterizing complex mixtures’ chemical composition.
Proteomics
The large-scale study of proteins, which are large, complex molecules that are required for structure, function, and regulation of the human body's tissues and organs.
Leukocyte Genomics
A leukocyte is a colorless cell circulating in the blood and body fluids and is involved in counteracting foreign substances and disease. A genome is all genetic material of an organism. Genomics is a biology field focusing on the structure, function, evolution, mapping, and editing of genomes. Therefore, leukocyte genomics is the study of all genetic material of leukocytes.
Metabolomics
Metabolomics is a way to study metabolism – that is, through measuring amounts of the metabolites (small molecules) produced by our bodies as we convert food into energy and other molecules that our cells need to survive. Metabolomics technology is ‘large-scale,’ meaning that several thousand metabolites can be measured from a single sample of e.g., blood or urine.
Micro RNA
Cells use Micro RNA to control whether a particular gene is making too much, too little or the normal amount of its protein at a particular time.
Autoantibodies
Antibodies that react with self-molecules and that occur in healthy individuals and are referred to as natural antibodies or autoantibodies.
Extracellular DNA for viral reactivation and Mitochondrial DNA
exDNA (extracellular DNA), exDNA is often secreted actively and is used to perform several tasks, thereby offering an attractive target or tool for biotechnological, medical, environmental, and general microbiological applications. Viruses are intracellular parasites that rely to a significant extent on the host cell for replication. Viral reactivation occurs when an active replication of the viral genome results in a lytic (degradation of the cell) infection characterized by the release of new progeny (descendant) virus particles.
Immune cell profiling
The immune system has many important regulatory roles in disease development and progression. Given the emergence of effective immune therapies, reliable predictors of response are needed. Immune cell profiling determines response by evaluating immune cell populations from treated and untreated samples. For our purposes, we will evaluate the white blood cell response to the viral infection using a process called “Cytof.”