Announcing OMF's First ME/CFS Clinical Trial!

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Driving research of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS),
Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia and Long COVID.

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when there is a BIOMARKER a TREATMENT a CURE

Now, imagine it 3x faster

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Every donation brings us one step closer toward finding diagnostic tests and treatments for ME/CFS and Long COVID. Now is the time to have your gift tripled.

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All donations will be tripled up to $500,000!

What Is Triple Giving November?

Triple Giving November is our biggest fundraising event of the year. Thanks to generous matching donors, ALLgifts made to OMFCA will be tripled up to $500,000 until November 30, 2023.

Regardless of how, when, or where you donate, your gift will be tripled up to $500,000. Every day of the week!

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What do your donations fund?

Every donation brings us one step closer toward finding diagnostic tests, treatments, and a cure.

SEVEN
COLLABORATIVE CENTERS

OMF’s strategy focuses on collaboration so that precise diagnostic tools, life-changing treatments, and knowledgeable physicians can be available to people with chronic complex diseases as soon as possible.

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WORLD CLASS
SCIENTIFIC ADVISORY BOARD

OMF’s Scientific Advisory Board is an alliance of world-renowned researchers.They dedicate their time, passion, and expertise to ending ME/CFS, Long COVID,  and related diseases.

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GROUNDBREAKING
LONG COVID RESEARCH

OMF researchers have launched an international study on COVID-19’s potential conversion to ME/CFS (“Long COVID”). This research provides incredible insight into the disease process. OMF’s goal is to find treatments and prevention strategies at an accelerated pace.

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MEDICAL EDUCATION
RESOURCE CENTER (MERC)

In partnership with Bateman Horne Center, The OMF Supported MERC will increase access to knowledgeable healthcare providers and improve patient care.

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The OMF Difference

In 2006, OMF Founder & CEO Linda Tannenbaum’s 16-year-old daughter went from being a healthy teenager to severely ill overnight. She could not get out of bed, and all her energy had been drained. Her daughter had sudden onset ME/CFS. After visiting over 20 doctors, Linda quickly realized there was a huge gap in research – no treatments, diagnostics, or cure for ME/CFS exists.

In 2012, Linda set out to change this. She established OMF as a nonprofit organization with a mission to fundraise and facilitate large-scale research in search of diagnostic tools, treatments, and ultimately a cure. OMF’s board members, staff and volunteers that include patients and caregivers inspire, advise, and dedicate their time to this mission.

By 2014, Linda and renowned geneticist Ronald W. Davis, PhD, also a parent of a severely ill son, joined forces. Together they built OMF’s Scientific Advisory Board (SAB) of leading experts dedicated to our mission.

OMF has since raised more than $45 million and leads the largest worldwide nonprofit effort to end ME/CFS and Long Covid. United by passion and scientific curiosity, our OMF Collaborative Research Network will not give up until answers are found. Your support ensures their success.

TRIPLE GIVING NOVEMBER

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Microvesicles and viral sequencing
Microvesicles are a type of extracellular vesicle that is released from the cell membrane. Vesicles are small, fluid-filled sacs or vacuoles within the body. Sequencing is a technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA (or viral) molecule.
NMR Metabolomics
NMR (Nuclear Magnetic Resonance) is an instrument/tool used to perform metabolic studies, metabolic profiling, and metabolomics in biofluids and tissues for more than 40 years using magnetic fields. There is a very close connection between metabolic measurements and NMR. This connection has flourished because of NMR’s many unique strengths for characterizing complex mixtures’ chemical composition.
Proteomics
The large-scale study of proteins, which are large, complex molecules that are required for structure, function, and regulation of the human body's tissues and organs.
Leukocyte Genomics
A leukocyte is a colorless cell circulating in the blood and body fluids and is involved in counteracting foreign substances and disease. A genome is all genetic material of an organism. Genomics is a biology field focusing on the structure, function, evolution, mapping, and editing of genomes. Therefore, leukocyte genomics is the study of all genetic material of leukocytes.
Metabolomics
Metabolomics is a way to study metabolism – that is, through measuring amounts of the metabolites (small molecules) produced by our bodies as we convert food into energy and other molecules that our cells need to survive. Metabolomics technology is ‘large-scale,’ meaning that several thousand metabolites can be measured from a single sample of e.g., blood or urine.
Micro RNA
Cells use Micro RNA to control whether a particular gene is making too much, too little or the normal amount of its protein at a particular time.
Autoantibodies
Antibodies that react with self-molecules and that occur in healthy individuals and are referred to as natural antibodies or autoantibodies.
Extracellular DNA for viral reactivation and Mitochondrial DNA
exDNA (extracellular DNA), exDNA is often secreted actively and is used to perform several tasks, thereby offering an attractive target or tool for biotechnological, medical, environmental, and general microbiological applications. Viruses are intracellular parasites that rely to a significant extent on the host cell for replication. Viral reactivation occurs when an active replication of the viral genome results in a lytic (degradation of the cell) infection characterized by the release of new progeny (descendant) virus particles.
Immune cell profiling
The immune system has many important regulatory roles in disease development and progression. Given the emergence of effective immune therapies, reliable predictors of response are needed. Immune cell profiling determines response by evaluating immune cell populations from treated and untreated samples. For our purposes, we will evaluate the white blood cell response to the viral infection using a process called “Cytof.”