Driving research of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS),
Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia and Post COVID .

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2022 review
Looking Back & Looking Forward:
OMF's 2022 Year in Review

Thank you for helping us to make this past year one of much progress. In 2023, we will continue to scale our efforts as we pave the way for a brighter future for all those impacted by multi-system chronic, complex diseases (msCCD).

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A Cure Is Out There

People with Chronic Complex Diseases deserve the right to live full, productive lives.

Scientific
Advisory Board
Scientific
Advisory Board
Scientific
Advisory Board
An Alliance of
Brilliant Scientific Minds

19 World-renowned scientists

2 Nobel Laureates

6 National Academy of Sciences Members

World-Class Research

6 OMF established ME / CFS Collaborative Research Centers

OMF Awarded Score of 100
on Charity Navigator!

OMF’s score of 100 serves as an indicator of trust, demonstrating our longstanding commitment to ensuring accountability, transparency, and measures of financial health, including stability, efficiency and sustainability.

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OMF and OMFCA ACCELERATE RESEARCH ACROSS THE GLOBE

Since our inception in 2012, Open Medicine Foundation (OMF) has raised over $40 million to fund open and collaborative research and improve health care for millions suffering with multi-system chronic, complex diseases (msCCD). Our disease focus includes Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS), Long COVID, Post-Treatment Lyme Disease, and Fibromyalgia.

We have facilitated and funded the establishment of 7 collaborative centers across the globe, in four countries and three continents. These centers are dedicated to diagnosing, treating, and ultimately curing these related chronic, complex diseases. 

Open Medicine Foundation is a US-based global nonprofit, with an affiliate organization in Canada (OMF Canada) and a foreign branch in Australia (OMF Australia Ltd). OMF Canada received Charity Status from the Canada Revenue Agency on June 6, 2019. We launched our relationship with the Collaborative Research Center at CHU Sainte-Justine /Université de Montréal on December 11, 2019.

Our 19 member Scientific Advisory Board is world renowned and includes two Nobel laureates and six National Academy of Sciences members.

OMF Supported Collaborative Centers

ME / CFS Collaborative Research Center

at the CHU Sainte-Justine/
Université de Montréal

Alain Moreau, PhD
Director

Clinical and scientific intervention studies

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ME / CFS Collaborative
Research Center

at Stanford

Ronald W. Davis, PhD
Director

Innovative, collaborative, multi-disciplinary research

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The Ronald G. Tompkins
Harvard ME / CFS Collaboration

at Harvard Affiliated Hospitals

Wenzhong Xiao, PhD
Co-Director

David Systrom, MD
Co-Director

Clinical and scientific mechanistic studies towards discovering new treatments

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ME / CFS Collaborative
Research Center

at Uppsala, Sweden

Jonas Bergquist, MD, PhD
Director

Research for biomarkers in body and brain

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Melbourne ME / CFS Collaboration

Chris Armstrong, PhD
Director

Precision research program

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Computational
Research Center
for Complex Diseases

Wenzhong Xiao, PhD
Director

From data to disease mechanism and treatments

 
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OMF Supported Medical Education Resource Center (MERC)

at Bateman Horne Center

Lucinda Bateman, MD
Medical Education Director

A global initiative to increase access to knowledgeable healthcare providers and improve patient care.

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Find Out More About ME / CFS
Our Current Projects Read more
Clinical Management Resources

ME / CFS and Covid-19
Research Study

The six, OMF funded, ME / CFS Collaborative Research Centres have launched an international study of the possible conversion of COVID-19 patients to ME / CFS.

This study, which seeks to learn about the pathways involved in the development of ME / CFS, can lead to biomarkers, new treatments, and prevention strategies.

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Latest News

OMF Scientific Advisory Board

An Alliance with Brilliant Scientific Minds

19 world-renowned scientists

2 Nobel laureates

6 National Academy
of Sciences members

Find Out More

Research Interviews

Researh Interviews

11 Videos

Join our Fight to Ignite ME / CFS Research
Across the Globe!

OMF’s international community —
united by a shared commitment to find answers to end ME / CFS and related multi-system chronic, complex diseases (msCCD).

The Faces of ME / CFS
What is ME / CFS?
Join OMF Canada to Find A Cure

Take Action Now!

Please help us expand our research efforts across the globe. 
Every donation brings us closer to a fully funded research effort and the answers we all seek.

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"Our donors want to stop millions from suffering and have come to expect research with impeccable credibility. The time is now to attract the kind of serious investment that will speed up our search for a cure and end these debilitating diseases."

Linda Tannenbaum, OMF Founder & CEO/President

*Qualified donees are as follows:

  • a registered charity (including a registered national arts service organization)
  • a registered Canadian amateur athletic association
  • a registered housing corporation resident in Canada constituted exclusively to provide low-cost housing for the aged
  • a registered Canadian municipality
  • a registered municipal or public body performing a function of government in Canada
  • a registered university outside Canada, the student body of which ordinarily includes students from Canada
  • a registered charitable organization outside Canada to which Her Majesty in right of Canada has made a gift
  • Her Majesty in right of Canada, a province, or a territory
  • the United Nations and its agencies
NMR Metabolomics
NMR (Nuclear Magnetic Resonance) is an instrument/tool used to perform metabolic studies, metabolic profiling, and metabolomics in biofluids and tissues for more than 40 years using magnetic fields. There is a very close connection between metabolic measurements and NMR. This connection has flourished because of NMR’s many unique strengths for characterizing complex mixtures’ chemical composition.
Proteomics
The large-scale study of proteins, which are large, complex molecules that are required for structure, function, and regulation of the human body's tissues and organs.
Microvesicles and viral sequencing
Microvesicles are a type of extracellular vesicle that is released from the cell membrane. Vesicles are small, fluid-filled sacs or vacuoles within the body. Sequencing is a technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA (or viral) molecule.
Micro RNA
Cells use Micro RNA to control whether a particular gene is making too much, too little or the normal amount of its protein at a particular time.
Autoantibodies
Antibodies that react with self-molecules and that occur in healthy individuals and are referred to as natural antibodies or autoantibodies.
Extracellular DNA for viral reactivation and Mitochondrial DNA
exDNA (extracellular DNA), exDNA is often secreted actively and is used to perform several tasks, thereby offering an attractive target or tool for biotechnological, medical, environmental, and general microbiological applications. Viruses are intracellular parasites that rely to a significant extent on the host cell for replication. Viral reactivation occurs when an active replication of the viral genome results in a lytic (degradation of the cell) infection characterized by the release of new progeny (descendant) virus particles.
Immune cell profiling
The immune system has many important regulatory roles in disease development and progression. Given the emergence of effective immune therapies, reliable predictors of response are needed. Immune cell profiling determines response by evaluating immune cell populations from treated and untreated samples. For our purposes, we will evaluate the white blood cell response to the viral infection using a process called “Cytof.”
Leukocyte Genomics
A leukocyte is a colorless cell circulating in the blood and body fluids and is involved in counteracting foreign substances and disease. A genome is all genetic material of an organism. Genomics is a biology field focusing on the structure, function, evolution, mapping, and editing of genomes. Therefore, leukocyte genomics is the study of all genetic material of leukocytes.
Metabolomics
Metabolomics is a way to study metabolism – that is, through measuring amounts of the metabolites (small molecules) produced by our bodies as we convert food into energy and other molecules that our cells need to survive. Metabolomics technology is ‘large-scale,’ meaning that several thousand metabolites can be measured from a single sample of e.g., blood or urine.