Skeletal Muscle Dysfunction
This project aims to explore the biological changes that occur in the muscles during Post-exertional Malaise (PEM).
Investigation into Post-Exertional Malaise Between Historical and Recent ME/CFS
The study expands on a previously-awarded proposal to thoroughly explore the underlying pathophysiology of post exertional malaise (PEM), the hallmark symptom of ME/CFS.
Sleep Disturbance in ME/CFS
Sleep Disturbance in ME/CFS Study AIM We intend to examine multiple sleep studies that have been conducted in the past two years and performed at the MGH Neurology Sleep Medicine Laboratory in well characterized patients with ME/CFS. LEAD INVESTIGATORS Wenzhong Xiao, PhD Janet Mullington, PhD Donna Felsenstein, MD Updates and Potential IRB approval received for […]
Mestinon Clinical Trial
This clinical trial will test the exercise response to Mestinon in people with ME/CFS.
Heart Preload Failure
This study aims to evaluate different explanations of preload failure in ME/CFS patients.