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Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS) Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia Leading Research. Delivering Hope.Open Medicine Foundation® Canada

The Life Improvement Trial (LIFT)

Headshots of Jonas Bergquist and David Systrom alongside the text “The LIFT.”

The Life Improvement Trial (LIFT) aims to investigate two drugs, separately and in combination, Pyridostigmine (commonly known as Mestinon) and Low-Dose Naltrexone (LDN), for efficacy and to research the difference between responders and non-responders.

Skeletal Muscle Dysfunction

This project aims to explore the biological changes that occur in the muscles during Post-exertional Malaise (PEM).

Sleep Disturbance in ME/CFS

Sleep Disturbance in ME/CFS Study AIM We intend to examine multiple sleep studies that have been conducted in the past two years and performed at the MGH Neurology Sleep Medicine Laboratory in well characterized patients with ME/CFS. LEAD INVESTIGATORS Wenzhong Xiao, PhD Janet Mullington, PhD Donna Felsenstein, MD Updates and Potential IRB approval received for […]

Heart Preload Failure

This study aims to evaluate different explanations of preload failure in ME/CFS patients.

Personalized Automated Symptom Summary (PASS)​

Researchers are developing a tool to help clinicians more efficiently define the character and priorities of a patient’s current symptoms of ME/CFS, Post-Treatment Lyme Disease, or Fibromyalgia.