Investigation into Post-Exertional Malaise Between Historical and Recent ME/CFS

The study expands on a previously-awarded proposal to thoroughly explore the underlying pathophysiology of post exertional malaise (PEM), the hallmark symptom of ME/CFS.
Mestinon Clinical Trial

This clinical trial will test the exercise response to Mestinon in people with ME/CFS.
Skeletal Muscle Dysfunction

This project aims to explore the biological changes that occur in the muscles during Post-exertional Malaise (PEM).
Heart Preload Failure

This study aims to evaluate different explanations of preload failure in ME/CFS patients.