Driving research of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS),
Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia and Post COVID .

Skeletal Muscle Dysfunction

This project aims to explore the biological changes that occur in the muscles during Post-exertional Malaise (PEM).

Sleep Disturbance in ME/CFS

Sleep Disturbance in ME/CFS Study AIM We intend to examine multiple sleep studies that have been conducted in the past two years and performed at the MGH Neurology Sleep Medicine Laboratory in well characterized patients with ME/CFS. LEAD INVESTIGATORS Wenzhong Xiao, PhD Janet Mullington, PhD Donna Felsenstein, MD Updates and Potential IRB approval received for […]

Heart Preload Failure

This study aims to evaluate different explanations of preload failure in ME/CFS patients.

Personalized Automated Symptom Summary (PASS)​

Researchers are developing a tool to help clinicians more efficiently define the character and priorities of a patient’s current symptoms of ME/CFS, Post-Treatment Lyme Disease, or Fibromyalgia.