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Category: News

New Study from the ME/CFS Collaborative Center at Uppsala: Altered Metabolic Pathways in ME/CFS

The image depicts a grand building at Uppsala University, showcasing classic architectural design. The edifice features a symmetrical façade with arched windows on the ground floor and rectangular windows on the upper floors, all framed with decorative moldings.

The Heart of the Matter The ME/CFS Collaborative Center at Uppsala published an article on altered metabolic pathways in ME/CFS. The tryptophan metabolic pathway is highly relevant to ME/CFS because of its roles in immune function, neurotransmission, and energy metabolism. Untargeted and targeted analysis of metabolites revealed significant changes in metabolic networks of ME/CFS patients […]

Life Improvement Trial (LIFT) has officially begun!

This image features Jonas Bergquist and David Systrom’s portraits within circular frames, each bordered by a blue outline.

The Life Improvement Trial (LIFT) has officially begun! Conducting a proper clinical trial and ensuring all logistics are set up takes time, so we are excited to share that Open Medicine Foundation’s Life Improvement Trial (LIFT) has officially launched. Recruitment and screening began in August and the first participants have now been enrolled. What is […]

Watch Now: Recordings from the Portugal ME/CFS and Long COVID Conference!

Picture of Linda Tannenbaum, Jonas Bergquist, David Systrom, and Wenzhong Xiao standing next to a banner for the 1st International Conference on ME/CFS and Long COVID in Portugal.

We are pleased to share that recordings from the 1st International Conference on Clinical and Scientific Advances in ME/CFS and Long COVID are now available! This event, the first in Portugal, brought together leading scientists, clinicians, and international experts to share and discuss the latest biomedical evidence and findings on ME/CFS and the nexus between […]

Celebrating a Milestone: StudyME Registry Surpasses 10,000 Participants!

The image features the StudyME logo at the top left, which includes a stylized globe of interconnected circles in blue and teal, accompanied by the text "StudyME." Below the logo, a group of eight diverse, smiling individuals stands together, suggesting community and collaboration. At the bottom, the text reads: "Help us reach 100,000 participants!"

  Join us in making a difference: Sign up today and be a part of the solution! Let’s celebrate! We are thrilled to share a monumental milestone with you: OMF StudyME Registry has now surpassed 10,000 participants!   In April 2023, we proudly launched OMF StudyME, a participant registry powered by StudyPages. This innovative recruitment […]

Insights into Severe ME/CFS: Honoring Severe ME/CFS Awareness Day

The image shows Whitney laying in a bed on a brown pillow, looking directly at the camera. On the right side of his chest, he has a medical tube attached with green tape.

Today, August 8, we unite to honor Severe ME/CFS Awareness Day. This year, we raise awareness through the lens of Whitney Dafoe. Whitney, son of Ron Davis, PhD, and Janet Dafoe, PhD, is an extraordinary soul whose ME/CFS journey has been one of heart-wrenching challenges and remarkable courage.  Since 2004, this disease has tested his limits, […]

Celebrating 2 Years of MERC: Transforming Medical Education for ME/CFS and Long COVID

The image is a collage of three scenes featuring medical professionals. Left: Medical students and professionals in a discussion around a table. Middle: Three doctors smiling and conversing in a hospital environment. Right: A doctor on a couch consulting with two young women in a casual setting, with a world map design on the wall behind them.

  In 2022, we set out to educate healthcare professionals about diagnosing and managing ME/CFS and other chronic complex diseases.   Today, we are thrilled to celebrate the successful completion of the second year of the Medical Education Resource Center (MERC) at Bateman Horne Center, supported by Open Medicine Foundation (OMF). Here is a snapshot of […]

Join Theresa in Building Hope for ME/CFS Research!

The picture shows Erica, wearing glasses and a navy blue patterned dress, smiling and seated on a green plastic chair on a grassy lawn. Next to her, a black dog with a pink collar rests on the ground.

Imagine a life where your everyday dreams suddenly become a distant memory. For Erica, a vibrant young adult diagnosed with ME/CFS at just 14, the journey has been a relentless battle against fatigue, migraines, and cognitive dysfunction. Her aspirations for university, a career, and a family life were dramatically altered. Yet, her unwavering spirit and […]

Groundbreaking Awareness and Fundraising: Physics Girl Livestream’s Incredible Results

Dianna Cowern sitting on a high stool against a solid blue background. She has long blond hair and is smiling, giving a joyful and relaxed vibe.

We are overflowing with gratitude and hope following the incredible live-streaming event hosted by Dianna Cowern (Physics Girl) and her outstanding team. Your engagement and generosity have shattered our expectations. What started as a goal to raise $10,000 turned into a mind-blowing $121,983 fundraiser and still growing! Missed the Live Event? Watch It Now! Dianna’s […]

Join Physics Girl’s Livestream: A Day in the Life with Long COVID and ME/CFS

Dianna Cowern sitting on a high stool against a solid blue background. She has long blond hair and is smiling, giving a joyful and relaxed vibe.

If you are a science enthusiast, you have probably heard of Dianna Cowern, an American science communicator and YouTuber known as Physics Girl, who is living with Long COVID and ME/CFS.  This Saturday (July 6, 2024), Dianna’s team will be live-streaming a day in her life, showcasing what it’s like for her to suffer from […]

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Microvesicles and viral sequencing
Microvesicles are a type of extracellular vesicle that is released from the cell membrane. Vesicles are small, fluid-filled sacs or vacuoles within the body. Sequencing is a technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA (or viral) molecule.
NMR Metabolomics
NMR (Nuclear Magnetic Resonance) is an instrument/tool used to perform metabolic studies, metabolic profiling, and metabolomics in biofluids and tissues for more than 40 years using magnetic fields. There is a very close connection between metabolic measurements and NMR. This connection has flourished because of NMR’s many unique strengths for characterizing complex mixtures’ chemical composition.
Proteomics
The large-scale study of proteins, which are large, complex molecules that are required for structure, function, and regulation of the human body's tissues and organs.
Autoantibodies
Antibodies that react with self-molecules and that occur in healthy individuals and are referred to as natural antibodies or autoantibodies.
Extracellular DNA for viral reactivation and Mitochondrial DNA
exDNA (extracellular DNA), exDNA is often secreted actively and is used to perform several tasks, thereby offering an attractive target or tool for biotechnological, medical, environmental, and general microbiological applications. Viruses are intracellular parasites that rely to a significant extent on the host cell for replication. Viral reactivation occurs when an active replication of the viral genome results in a lytic (degradation of the cell) infection characterized by the release of new progeny (descendant) virus particles.
Immune cell profiling
The immune system has many important regulatory roles in disease development and progression. Given the emergence of effective immune therapies, reliable predictors of response are needed. Immune cell profiling determines response by evaluating immune cell populations from treated and untreated samples. For our purposes, we will evaluate the white blood cell response to the viral infection using a process called “Cytof.”
Leukocyte Genomics
A leukocyte is a colorless cell circulating in the blood and body fluids and is involved in counteracting foreign substances and disease. A genome is all genetic material of an organism. Genomics is a biology field focusing on the structure, function, evolution, mapping, and editing of genomes. Therefore, leukocyte genomics is the study of all genetic material of leukocytes.
Metabolomics
Metabolomics is a way to study metabolism – that is, through measuring amounts of the metabolites (small molecules) produced by our bodies as we convert food into energy and other molecules that our cells need to survive. Metabolomics technology is ‘large-scale,’ meaning that several thousand metabolites can be measured from a single sample of e.g., blood or urine.
Micro RNA
Cells use Micro RNA to control whether a particular gene is making too much, too little or the normal amount of its protein at a particular time.