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Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS) Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia Leading Research. Delivering Hope.Open Medicine Foundation® Canada
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Our Big Bold Vision
Create a world where people with Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS) and other related chronic diseases live life fully.  
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Our Mission​​
Cure chronic diseases and provide more than 560,000 Canadians with ME/CFS the opportunity to live full, productive lives.
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Fundraise to facilitate open, collaborative research to find effective treatments, diagnostic markers, and ultimately a cure for chronic complex disease patients in Canada.
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Fundraise critical donations to accelerate research to improve the lives of all persons living with chronic diseases. Join our OMF Canada family.  Donate to accelerate research today.
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Current Research

Open Medicine Foundation Canada fundraises for innovative research required to cure ME/CFS and related chronic diseases. Read about the research underway at the OMF funded Collaborative Research Centres at Stanford, Harvard, and more.

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Understanding the Disease

ME/CFS and chronic diseases are often misunderstood and stigmatized. Our team of world-renowned researchers and clinicians undertake a collaborative and open approach to solving what is a little understood disease afflicting millions. Learn about ME/CFS.

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News

Read the latest research news, foundation announcements, media coverage, and more, to learn what you are supporting.

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Help create a world without Myalgic Encephomyalitis, commonly known as Chronic Fatigue Syndrome (ME/CFS) by getting involved how it best suits YOU! 

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What is ME/CFS
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Collaborative Research Centres

Harvard

Clinical and scientific mechanistic studies to understand ME/CFS and discover new treatments

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Stanford

Innovative, collaborative, open-data research to end ME/CFS


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Other Research

OMF Canada is funding research to understand the biological cause, effective treatments, and ultimately a cure for ME/CFS and chronic diseases.
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Consent management

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Data Subject Access Request (DSAR) Form 

Microvesicles and viral sequencing
Microvesicles are a type of extracellular vesicle that is released from the cell membrane. Vesicles are small, fluid-filled sacs or vacuoles within the body. Sequencing is a technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA (or viral) molecule.
NMR Metabolomics
NMR (Nuclear Magnetic Resonance) is an instrument/tool used to perform metabolic studies, metabolic profiling, and metabolomics in biofluids and tissues for more than 40 years using magnetic fields. There is a very close connection between metabolic measurements and NMR. This connection has flourished because of NMR’s many unique strengths for characterizing complex mixtures’ chemical composition.
Proteomics
The large-scale study of proteins, which are large, complex molecules that are required for structure, function, and regulation of the human body's tissues and organs.
Autoantibodies
Antibodies that react with self-molecules and that occur in healthy individuals and are referred to as natural antibodies or autoantibodies.
Extracellular DNA for viral reactivation and Mitochondrial DNA
exDNA (extracellular DNA), exDNA is often secreted actively and is used to perform several tasks, thereby offering an attractive target or tool for biotechnological, medical, environmental, and general microbiological applications. Viruses are intracellular parasites that rely to a significant extent on the host cell for replication. Viral reactivation occurs when an active replication of the viral genome results in a lytic (degradation of the cell) infection characterized by the release of new progeny (descendant) virus particles.
Immune cell profiling
The immune system has many important regulatory roles in disease development and progression. Given the emergence of effective immune therapies, reliable predictors of response are needed. Immune cell profiling determines response by evaluating immune cell populations from treated and untreated samples. For our purposes, we will evaluate the white blood cell response to the viral infection using a process called “Cytof.”
Leukocyte Genomics
A leukocyte is a colorless cell circulating in the blood and body fluids and is involved in counteracting foreign substances and disease. A genome is all genetic material of an organism. Genomics is a biology field focusing on the structure, function, evolution, mapping, and editing of genomes. Therefore, leukocyte genomics is the study of all genetic material of leukocytes.
Metabolomics
Metabolomics is a way to study metabolism – that is, through measuring amounts of the metabolites (small molecules) produced by our bodies as we convert food into energy and other molecules that our cells need to survive. Metabolomics technology is ‘large-scale,’ meaning that several thousand metabolites can be measured from a single sample of e.g., blood or urine.
Micro RNA
Cells use Micro RNA to control whether a particular gene is making too much, too little or the normal amount of its protein at a particular time.