STUDY HYPOTHESIS AND DESCRIPTION
Combined with clinical data and survey data, this massive data set should provide a significant picture to understand post-viral diseases.
- Energy metabolism markers during mild mental and physical exertion analyzed on-site inpatient homes with immediate analysis of samples.
- Samples collected every 5-15 minutes over 6-7 hours, monitoring in real time baseline compared to longitudinal data.
- Complement this with full metabolomics screening to compare and contrast the findings in metabolic/mitochondrial disturbances over time.
- Targeting 25 PWME (ell/SIPS) + 25 Controls + 25 Contrast (elite athletes)

OBJECTIVES
- Pattern biology that corresponds to patient symptoms over the course of a day in two international cohorts (Sweden, Australia)
- Track the biological impact of meals, social tasks, mental tasks, and exercise tasks, on ME/CFS patients compared to controls
- Cluster patients based on similar biology-symptom dynamics.