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Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS) Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia Leading Research. Delivering Hope.Open Medicine Foundation® Canada

Home Visit Study

  • IRB approval completed.
  • Over 3000 samples collected, and each will be initially analyzed with MS metabolomics (and potentially with NMR if needed).

STUDY HYPOTHESIS AND DESCRIPTION

Combined with clinical data and survey data, this massive data set should provide a significant picture to understand post-viral diseases.

  • Energy metabolism markers during mild mental and physical exertion analyzed on-site inpatient homes with immediate analysis of samples.
  • Samples collected every 5-15 minutes over 6-7 hours, monitoring in real time baseline compared to longitudinal data.
  • Complement this with full metabolomics screening to compare and contrast the findings in metabolic/mitochondrial disturbances over time.
  • Targeting 25 PWME (ell/SIPS) + 25 Controls + 25 Contrast (elite athletes)

Close up of gloved hands drawing blood from a patient.

OBJECTIVES

  • Pattern biology that corresponds to patient symptoms over the course of a day in two international cohorts (Sweden, Australia)
  • Track the biological impact of meals, social tasks, mental tasks, and exercise tasks, on ME/CFS patients compared to controls
  • Cluster patients based on similar biology-symptom dynamics.