Announcing OMF's First ME/CFS Clinical Trial!

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Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS) Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia Leading Research. Delivering Hope.Open Medicine Foundation® Canada

Driving research of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS),
Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia and Long COVID.

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Join the Hope Builders Challenge: Your Monthly Gift Can Ignite Change!

Imagine our collective strength when we unite for a cure. At Open Medicine Foundation Canada (OMFCA), we are driven to find effective treatments for ME/CFS and Long COVID. Our global collaboration model harnesses the brightest minds to bring relief to you and your loved ones.

 

A smiling woman with shoulder-length reddish-brown hair, accompanied by the Hope Builders logo.

Yet, this monumental task cannot be accomplished alone. This is where you step in. By becoming a Hope Builder, your monthly support can accelerate transformative research in 2024 and beyond. Join the Hope Builders community!

 

The Hope Builders Challenge

 

This March, we’ve set an audacious goal: to welcome 30 new monthly donors before the month’s end. This is the essence of the Hope Builders Challenge—an opportunity for you to be an integral part of a life-changing mission.

 

Your monthly commitment is the foundation of progress. It ensures a steady stream of resources to propel groundbreaking research, fuel our clinical trial program, fund medical education, and champion improved patient care and recognition. 

 

Every Gift is a Building Block for Progress

 

Consider the ripple effect: if 50 compassionate individuals like you contributed just $5 monthly, that would equal $3,000 a year—funds that could unlock new possibilities for treatments and a cure. Now is your moment to become an architect of hope.

 

Become a Hope Builder

We are deeply grateful for your unwavering spirit and generosity. Thank you for being a beacon of hope. Together, let’s unravel, support, empower, and expand for a healthier future. 

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Microvesicles and viral sequencing
Microvesicles are a type of extracellular vesicle that is released from the cell membrane. Vesicles are small, fluid-filled sacs or vacuoles within the body. Sequencing is a technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA (or viral) molecule.
NMR Metabolomics
NMR (Nuclear Magnetic Resonance) is an instrument/tool used to perform metabolic studies, metabolic profiling, and metabolomics in biofluids and tissues for more than 40 years using magnetic fields. There is a very close connection between metabolic measurements and NMR. This connection has flourished because of NMR’s many unique strengths for characterizing complex mixtures’ chemical composition.
Proteomics
The large-scale study of proteins, which are large, complex molecules that are required for structure, function, and regulation of the human body's tissues and organs.
Immune cell profiling
The immune system has many important regulatory roles in disease development and progression. Given the emergence of effective immune therapies, reliable predictors of response are needed. Immune cell profiling determines response by evaluating immune cell populations from treated and untreated samples. For our purposes, we will evaluate the white blood cell response to the viral infection using a process called “Cytof.”
Leukocyte Genomics
A leukocyte is a colorless cell circulating in the blood and body fluids and is involved in counteracting foreign substances and disease. A genome is all genetic material of an organism. Genomics is a biology field focusing on the structure, function, evolution, mapping, and editing of genomes. Therefore, leukocyte genomics is the study of all genetic material of leukocytes.
Metabolomics
Metabolomics is a way to study metabolism – that is, through measuring amounts of the metabolites (small molecules) produced by our bodies as we convert food into energy and other molecules that our cells need to survive. Metabolomics technology is ‘large-scale,’ meaning that several thousand metabolites can be measured from a single sample of e.g., blood or urine.
Micro RNA
Cells use Micro RNA to control whether a particular gene is making too much, too little or the normal amount of its protein at a particular time.
Autoantibodies
Antibodies that react with self-molecules and that occur in healthy individuals and are referred to as natural antibodies or autoantibodies.
Extracellular DNA for viral reactivation and Mitochondrial DNA
exDNA (extracellular DNA), exDNA is often secreted actively and is used to perform several tasks, thereby offering an attractive target or tool for biotechnological, medical, environmental, and general microbiological applications. Viruses are intracellular parasites that rely to a significant extent on the host cell for replication. Viral reactivation occurs when an active replication of the viral genome results in a lytic (degradation of the cell) infection characterized by the release of new progeny (descendant) virus particles.