Announcing OMF's First ME/CFS Clinical Trial!

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Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS) Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia Leading Research. Delivering Hope.Open Medicine Foundation® Canada

Driving research of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS),
Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia and Long COVID.

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David Systrom, MD, PhD
Co-Director – The Ronald G. Tompkins Harvard ME/CFS Collaboration

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Dr. David Systrom is a member of the Brigham and Women’s Hospital pulmonary and critical care faculty and Assistant Professor of Medicine at Harvard Medical School where he directs the Dyspnea Clinic and the Advanced Cardiopulmonary Exercise Testing Program. He has been on the Harvard faculty for over 35 years during which time he has received NIH, […]

Jack Emmett

Jack Emmett with trophy

Jack Emmett Professional Football Player About Jack At 27 years old, Jack Emmett has pursued a career in professional football (soccer) in England. Having played for the professional Association Football Club Harrogate Town as a midfielder for eight years, he has won two promotions to reach the football league for the first time in the […]

Brent Handle

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Brent Handel has been a lawyer for over 30 years and practices in the area of Civil Litigation and Insurance Law.  He was appointed a Queen’s Counsel (Q.C.) on December 30, 2011. This honorary title is intended to recognize a lawyer’s achievement and standing in the legal profession for quality work, professional integrity, and outstanding […]

Jacqueline Ko

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Jacqueline Ko O p e r a P e r f o r m e r, P r o d u c e r About Jacqueline Jacqueline Ko, OMF and OMF Canada Ambassador, is a multi-award-winning Canadian performer, producer, and disability advocate. She is known for her roles in opera, theatre, musical theatre and film, […]

Juan Santiago

Juan Santiago received his MS and PhD in Mechanical Engineering from the University of Illinois at Urbana-Champaign in 1995. His research includes the development of microsystems for on-chip chemical and biochemical analysis, methods for sample preparation, and electric-field based deionization methods. Applications of this work include molecular diagnostics, drug discovery, and the production of drinking […]

Karin Alvtegen

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Karin Alvtegen Author About Karin Karin Alvtegen, OMF Ambassador, is one of Scandinavia’s most widely read and appreciated authors. Karin is recognized for her psychological thrillers, which include Guilt, Missing, Betrayal, Shame, Sacrifice, and Shadow, and has established herself as a celebrated bestseller worldwide, with her books translated into more than 35 languages. Missing has […]

Amy Carlson

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Amy carlson F i l m & T V A c t r e s s About Amy Amy Carlson is an American television actress known for her role in the CBS television series, Blue Bloods, as well as roles in other television series and movies including Third Watch, Landline, Criminal Minds, NCIS, and Law […]

Stuart Murdoch

Stuart Murdoch, headshot

Stuart Murdoch Singer & Songwriter About Stuart Stuart is the lead singer and songwriter for the band, and he is also a composer, writer, filmmaker, and father. Some of his songs and his films reflect the struggles he has faced with ME / CFS when he became too ill to work or study for seven years.These songs […]

Marilyn Simon-Gersuk, Director of Communications & Development

Marilyn Simon-Gersuk has over three decades of experience in fundraising and non-profit management.  She has held professional positions at the national, regional and local level. She has led development teams of 2 to 20+ raising millions of dollars. Marilyn began working with OMF in 2012 as a volunteer using her non-profit management experience to help […]

Debby Husch, Administrative Manager

Debby Husch has worked in non-profit fundraising for two decades. In her prior role at a national healthcare organization, Debby provided support to a national network of over 40 chapters, fostering fundraising growth and enhancing organizational strength; she planned week-long conferences and more. Debby has extensive experience in special event and project management. At OMF, […]

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Microvesicles and viral sequencing
Microvesicles are a type of extracellular vesicle that is released from the cell membrane. Vesicles are small, fluid-filled sacs or vacuoles within the body. Sequencing is a technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA (or viral) molecule.
NMR Metabolomics
NMR (Nuclear Magnetic Resonance) is an instrument/tool used to perform metabolic studies, metabolic profiling, and metabolomics in biofluids and tissues for more than 40 years using magnetic fields. There is a very close connection between metabolic measurements and NMR. This connection has flourished because of NMR’s many unique strengths for characterizing complex mixtures’ chemical composition.
Proteomics
The large-scale study of proteins, which are large, complex molecules that are required for structure, function, and regulation of the human body's tissues and organs.
Immune cell profiling
The immune system has many important regulatory roles in disease development and progression. Given the emergence of effective immune therapies, reliable predictors of response are needed. Immune cell profiling determines response by evaluating immune cell populations from treated and untreated samples. For our purposes, we will evaluate the white blood cell response to the viral infection using a process called “Cytof.”
Leukocyte Genomics
A leukocyte is a colorless cell circulating in the blood and body fluids and is involved in counteracting foreign substances and disease. A genome is all genetic material of an organism. Genomics is a biology field focusing on the structure, function, evolution, mapping, and editing of genomes. Therefore, leukocyte genomics is the study of all genetic material of leukocytes.
Metabolomics
Metabolomics is a way to study metabolism – that is, through measuring amounts of the metabolites (small molecules) produced by our bodies as we convert food into energy and other molecules that our cells need to survive. Metabolomics technology is ‘large-scale,’ meaning that several thousand metabolites can be measured from a single sample of e.g., blood or urine.
Micro RNA
Cells use Micro RNA to control whether a particular gene is making too much, too little or the normal amount of its protein at a particular time.
Autoantibodies
Antibodies that react with self-molecules and that occur in healthy individuals and are referred to as natural antibodies or autoantibodies.
Extracellular DNA for viral reactivation and Mitochondrial DNA
exDNA (extracellular DNA), exDNA is often secreted actively and is used to perform several tasks, thereby offering an attractive target or tool for biotechnological, medical, environmental, and general microbiological applications. Viruses are intracellular parasites that rely to a significant extent on the host cell for replication. Viral reactivation occurs when an active replication of the viral genome results in a lytic (degradation of the cell) infection characterized by the release of new progeny (descendant) virus particles.