Announcing OMF's First ME/CFS Clinical Trial!

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Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS) Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia Leading Research. Delivering Hope.Open Medicine Foundation® Canada

Driving research of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS),
Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia and Long COVID.

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Linda Tannenbaum, Fondatrice & Présidente- Directrice Générale

Linda Tannenbaum est fondatrice et présidente-directrice générale de l’Open Medicine Foundation (OMF), un organisme indépendant à but non lucratif voué au financement et à la facilitation de la recherche scientifique ouverte et collaborative en vue de faire des percées cliniques pour les maladies chroniques complexes, comme l’encéphalomyélite myalgique/le syndrome de fatigue chronique (EM/SFC).

Mme Tannenbaum a fondé l’ OMF après que sa fille a soudainement commencé à souffrir d’EM/SFC. Consciente de l’absence de recherche collaborative ouverte et mondiale sur la maladie, elle a créé l’ OMF pour faciliter la recherche à grande échelle afin de trouver un remède à ces maladies chroniques complexes.

Conférencière accomplie, Mme Tannenbaum a prononcé des allocutions et a été l’une des principales conférencières dans le monde entier. Ses présentations ont suscité des réactions enthousiastes de la part de scientifiques, de cliniciens et de patients en raison de sa capacité à simplifier la science complexe et aussi en raison de son empathie passionnée pour les patients et leurs aidants. Mme Tannenbaum possède une formation en sciences avec une licence en bactériologie de l’UCLA et une licence de scientifique de laboratoire clinique.

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Microvesicles and viral sequencing
Microvesicles are a type of extracellular vesicle that is released from the cell membrane. Vesicles are small, fluid-filled sacs or vacuoles within the body. Sequencing is a technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA (or viral) molecule.
NMR Metabolomics
NMR (Nuclear Magnetic Resonance) is an instrument/tool used to perform metabolic studies, metabolic profiling, and metabolomics in biofluids and tissues for more than 40 years using magnetic fields. There is a very close connection between metabolic measurements and NMR. This connection has flourished because of NMR’s many unique strengths for characterizing complex mixtures’ chemical composition.
Proteomics
The large-scale study of proteins, which are large, complex molecules that are required for structure, function, and regulation of the human body's tissues and organs.
Immune cell profiling
The immune system has many important regulatory roles in disease development and progression. Given the emergence of effective immune therapies, reliable predictors of response are needed. Immune cell profiling determines response by evaluating immune cell populations from treated and untreated samples. For our purposes, we will evaluate the white blood cell response to the viral infection using a process called “Cytof.”
Leukocyte Genomics
A leukocyte is a colorless cell circulating in the blood and body fluids and is involved in counteracting foreign substances and disease. A genome is all genetic material of an organism. Genomics is a biology field focusing on the structure, function, evolution, mapping, and editing of genomes. Therefore, leukocyte genomics is the study of all genetic material of leukocytes.
Metabolomics
Metabolomics is a way to study metabolism – that is, through measuring amounts of the metabolites (small molecules) produced by our bodies as we convert food into energy and other molecules that our cells need to survive. Metabolomics technology is ‘large-scale,’ meaning that several thousand metabolites can be measured from a single sample of e.g., blood or urine.
Micro RNA
Cells use Micro RNA to control whether a particular gene is making too much, too little or the normal amount of its protein at a particular time.
Autoantibodies
Antibodies that react with self-molecules and that occur in healthy individuals and are referred to as natural antibodies or autoantibodies.
Extracellular DNA for viral reactivation and Mitochondrial DNA
exDNA (extracellular DNA), exDNA is often secreted actively and is used to perform several tasks, thereby offering an attractive target or tool for biotechnological, medical, environmental, and general microbiological applications. Viruses are intracellular parasites that rely to a significant extent on the host cell for replication. Viral reactivation occurs when an active replication of the viral genome results in a lytic (degradation of the cell) infection characterized by the release of new progeny (descendant) virus particles.