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Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS) Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia Leading Research. Delivering Hope.Open Medicine Foundation® Canada
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Act Now: Your Year-End Donation Matters

Imagine a future where both ME/CFS and Long COVID are no longer debilitating conditions. Imagine the challenges in understanding, diagnosing, and finding effective treatments are a thing of the past. At Open Medicine Foundation Canada (OMFCA), we’re committed to turning that future into a reality. 

Thanks to the unwavering support of our community, we’ve made significant strides. We have raised over $49 million USD and funded 58 projects to date. These projects have resulted in 28 publications, and many more are on the horizon!

 

Your support is not just valuable; it’s essential to bringing this vision to life. Make your end-of-year donation today and be part of our global effort to bring millions back to health. 

Donate now

In 2023 alone, you helped us make the following possible:

  • Over 36 active research projects currently underway. These projects span various aspects of medical research, and each one holds the potential to make a significant impact in advancing our understanding of ME/CFS and Long COVID. 
  • Medical education that is increasing awareness, improving diagnosis, and fostering a more empathetic approach towards those suffering from these conditions. Through our Medical Education Resource Center (MERC), in partnership with Bateman Horne Center, we have already reached thousands of healthcare providers. 
  • OMF’s StudyME Registry: A global participant registry. OMF’s StudyME Registry is a recruitment tool to connect individuals interested in participating in research studies of ME/CFS and Long COVID with the researchers conducting them.
  • Clinical Trials: We are launching our first clinical trial, The Life Improvement Trial (LIFT). This trial will help us gather critical data on treatment responses and lay the groundwork for a robust clinical trial infrastructure for additional clinical trials in the coming years. 

An infographic chart shows OMF's 2023 milestones, including 36 active research projects, clinical trials, and the launch of OMF's StudyME Registry.

As we look to the new year, your donation isn’t just a gift; it’s a lifeline to millions. It’s a commitment to a future where no one has to miss out on life’s precious moments due to ME/CFS or Long COVID. It’s a step towards a world where these conditions are fully understood, effectively treated, and ultimately cured.

Donate now

Let us welcome 2024 with the promise of new possibilities, scientific discovery, and victories in our journey towards a brighter and healthier future. With each passing day, we are closer to achieving our goal, thanks to the unwavering commitment of supporters like you.

Thank you for being a part of our OMFCA Family.

Hold on to the HOPE,

 

Team OMFCA

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Microvesicles and viral sequencing
Microvesicles are a type of extracellular vesicle that is released from the cell membrane. Vesicles are small, fluid-filled sacs or vacuoles within the body. Sequencing is a technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA (or viral) molecule.
NMR Metabolomics
NMR (Nuclear Magnetic Resonance) is an instrument/tool used to perform metabolic studies, metabolic profiling, and metabolomics in biofluids and tissues for more than 40 years using magnetic fields. There is a very close connection between metabolic measurements and NMR. This connection has flourished because of NMR’s many unique strengths for characterizing complex mixtures’ chemical composition.
Proteomics
The large-scale study of proteins, which are large, complex molecules that are required for structure, function, and regulation of the human body's tissues and organs.
Autoantibodies
Antibodies that react with self-molecules and that occur in healthy individuals and are referred to as natural antibodies or autoantibodies.
Extracellular DNA for viral reactivation and Mitochondrial DNA
exDNA (extracellular DNA), exDNA is often secreted actively and is used to perform several tasks, thereby offering an attractive target or tool for biotechnological, medical, environmental, and general microbiological applications. Viruses are intracellular parasites that rely to a significant extent on the host cell for replication. Viral reactivation occurs when an active replication of the viral genome results in a lytic (degradation of the cell) infection characterized by the release of new progeny (descendant) virus particles.
Immune cell profiling
The immune system has many important regulatory roles in disease development and progression. Given the emergence of effective immune therapies, reliable predictors of response are needed. Immune cell profiling determines response by evaluating immune cell populations from treated and untreated samples. For our purposes, we will evaluate the white blood cell response to the viral infection using a process called “Cytof.”
Leukocyte Genomics
A leukocyte is a colorless cell circulating in the blood and body fluids and is involved in counteracting foreign substances and disease. A genome is all genetic material of an organism. Genomics is a biology field focusing on the structure, function, evolution, mapping, and editing of genomes. Therefore, leukocyte genomics is the study of all genetic material of leukocytes.
Metabolomics
Metabolomics is a way to study metabolism – that is, through measuring amounts of the metabolites (small molecules) produced by our bodies as we convert food into energy and other molecules that our cells need to survive. Metabolomics technology is ‘large-scale,’ meaning that several thousand metabolites can be measured from a single sample of e.g., blood or urine.
Micro RNA
Cells use Micro RNA to control whether a particular gene is making too much, too little or the normal amount of its protein at a particular time.