Search
Close this search box.
Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS) Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia Leading Research. Delivering Hope.Open Medicine Foundation® Canada

Crash-Course: Studying PEM/flares in ME/CFS, PTLDS, Long COVID

a close-up of a finger with a drop of blood on it, against a white background.

The study aims to compare biological markers during mild symptoms and flare/PEM events in individuals with ME/CFS, alongside PTLDS and Long COVID patients, using finger-prick blood samples and continuous data from wearable sensors to understand symptom variability.

25-Day Metabolite Monitoring Study of ME/CFS patients

The image depicts a healthcare professional in the process of collecting a blood sample from a patient. The professional is wearing blue gloves and a surgical mask, following proper sanitary protocols to ensure a sterile environment.

The study aims to meticulously analyze daily changes in metabolites from blood samples of individuals with ME/CFS over 25 days, to uncover the complex biological processes contributing to the condition and facilitate patient clustering by dynamic changes, thereby addressing the challenge of clinical and biological diversity within the ME/CFS population.

AusME Biobank Biomarker Project

a close-up of a gloved hand holding a test tube containing a blood sample. The test tube is labeled with barcode for identification and tracking purposes.

The study aims to utilize the Australian ME/CFS biobank for metabolomics analyses and other assays to identify potential biomarkers for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, contributing to a comprehensive dataset for large-scale analysis.

Temporally Resolved Omics Tracking of ME/CFS

Woman researcher doing a blood test

This study seeks to understand the biological mechanisms driving the symptomatology of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) using metabolomic and lipidomic high-throughput analysis and high-frequency blood sampling over a 6.5 to 7.5 hour period conducted at two separate sites (Melbourne and Uppsala).

Single Day Longitudinal Study

Doctor drawing blood

This study seeks to understand the biological mechanisms driving the symptomatology of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) using metabolomic and lipidomic high-throughput analysis and high-frequency blood sampling over a 6.5 to 7.5 hour period conducted at two separate sites (Melbourne and Uppsala).

Itaconate Trap Study

This project aims to look at metabolic traps in central carbon metabolism that lead to observed altered energy production pathways in ME/CFS.

Biological Outlier and Subtyping Software for Myalgic Encephalomyelitis

This project will develop a software tool to rapidly look for metabolism anomalies in an individual which might be explained by their genes. It will also look for potentially damaging genes in individuals and it will attempt to group ME/CFS patients based on their genetic and metabolic profiles.

Condensed Precision Medicine Protocol for ME/CFS

Male doctor holding lab results, holding up a finger pointing upwards

The study aims to establish a condensed personalized research protocol that can be used to characterize ME/CFS in individual patients as it pertains to all their unique biological aspects, interacting with a complex chronic disease.