Announcing OMF's First ME/CFS Clinical Trial!

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Driving research of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS),
Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia and Long COVID.

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Category: montreal news

Dr. Alain Moreau’s paper was named a Top 100 Scientific Reports paper in 2020!

Open Medicine Foundation Canada (OMFCA) is excited to share that Dr. Alain Moreau’s paper Profile of circulating microRNAs in myalgic encephalomyelitis and their relation to symptom severity, and disease pathophysiology, has been named one of the top 100 Scientific Reports papers in 2020!  Serving on OMF’s Scientific Advisory Board, Alain Moreau, Ph.D., is also Director of […]

Profile of circulating microRNAs in myalgic encephalomyelitis and their relation to symptom severity, and disease pathophysiology by Alain Moreau, PhD, Montreal Collaboration

From the desk of Dr. Alain Moreau, PhDDirector of the Collaborative Research Center at the CHU Sainte-Justine/Université de Montréal #TripleGivingTuesday Research Update Montréal ME/CFS Research CenterPaper Published in Scientific Reports On behalf of Open Medicine Foundation Canada (OMFCA), I am pleased to share that an article authored by my research team at the OMF funded ME / CFS […]

Promising Studies Underway at Montréal Research Center | #TripleGivingTuesday

From the desk of Dr. Alain Moreau, PhDDirector of the Collaborative Research Center at the CHU Sainte-Justine/Université de Montréal #TripleGivingTuesday Research Update Promising Research Underwayat Montréal Research Center I’m very pleased to share with you, a valued supporter of Open Medicine Foundation Canada (OMFCA), an update from my team at the OMF funded ME/CFS Collaborative Research […]

OMF Welcomes Alain Moreau, PhD, to our Scientific Advisory Board

Dr. Alain Moreau joins the OMF Scientific Advisory Board OMF is honored to welcome Canadian researcher, Dr. Alain Moreau, to our Scientific Advisory Board (SAB,) which is directed by Ronald W. Davis. PhD. “I initially decided to invite Dr. Moreau to join our ME / CFS Working Group because he demonstrated that he could take […]

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Microvesicles and viral sequencing
Microvesicles are a type of extracellular vesicle that is released from the cell membrane. Vesicles are small, fluid-filled sacs or vacuoles within the body. Sequencing is a technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA (or viral) molecule.
NMR Metabolomics
NMR (Nuclear Magnetic Resonance) is an instrument/tool used to perform metabolic studies, metabolic profiling, and metabolomics in biofluids and tissues for more than 40 years using magnetic fields. There is a very close connection between metabolic measurements and NMR. This connection has flourished because of NMR’s many unique strengths for characterizing complex mixtures’ chemical composition.
Proteomics
The large-scale study of proteins, which are large, complex molecules that are required for structure, function, and regulation of the human body's tissues and organs.
Leukocyte Genomics
A leukocyte is a colorless cell circulating in the blood and body fluids and is involved in counteracting foreign substances and disease. A genome is all genetic material of an organism. Genomics is a biology field focusing on the structure, function, evolution, mapping, and editing of genomes. Therefore, leukocyte genomics is the study of all genetic material of leukocytes.
Metabolomics
Metabolomics is a way to study metabolism – that is, through measuring amounts of the metabolites (small molecules) produced by our bodies as we convert food into energy and other molecules that our cells need to survive. Metabolomics technology is ‘large-scale,’ meaning that several thousand metabolites can be measured from a single sample of e.g., blood or urine.
Micro RNA
Cells use Micro RNA to control whether a particular gene is making too much, too little or the normal amount of its protein at a particular time.
Autoantibodies
Antibodies that react with self-molecules and that occur in healthy individuals and are referred to as natural antibodies or autoantibodies.
Extracellular DNA for viral reactivation and Mitochondrial DNA
exDNA (extracellular DNA), exDNA is often secreted actively and is used to perform several tasks, thereby offering an attractive target or tool for biotechnological, medical, environmental, and general microbiological applications. Viruses are intracellular parasites that rely to a significant extent on the host cell for replication. Viral reactivation occurs when an active replication of the viral genome results in a lytic (degradation of the cell) infection characterized by the release of new progeny (descendant) virus particles.
Immune cell profiling
The immune system has many important regulatory roles in disease development and progression. Given the emergence of effective immune therapies, reliable predictors of response are needed. Immune cell profiling determines response by evaluating immune cell populations from treated and untreated samples. For our purposes, we will evaluate the white blood cell response to the viral infection using a process called “Cytof.”