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 TRIPLE YOUR IMPACT during Triple Giving November | All Donations to OMFCA are TRIPLED through December 2

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Category: News

From OMF’s CEO, Linda Tannenbaum: A Message of Hope and Action

At OMF Canada (OMFCA), our purpose is clear: to revolutionize the way we understand and treat chronic complex multi-system diseases, with initial focus on ME/CFS and Long COVID, by illuminating their mechanisms, accelerating effective treatments, and empowering personalized care. Our mission is to drive and fund global collaborative research that unlocks disease biology, delivers precise […]

An Interview with Ron Davis, PhD and David Systrom, MD

As part of our Triple Giving November campaign, we’re pleased to share a new video interview with Dr. Ron Davis and Dr. David Systrom, two of OMF’s Directors. Together, they discuss how problems with oxygen supply and energy production may underlie ME/CFS. Triple My Gift An Interview with Ron Davis, PhD and David Systrom, MD:Low […]

Bring Hope to Nicky and Millions More

During Triple Giving November, every donation to Open Medicine Foundation Canada (OMFCA) will go three times as far to advance critical ME/CFS and Long COVID research. All gifts are tripled through December 2, 2025, up to $500,000. Make a Gift Today Meet Nicky: A Life Transformed by ME/CFS Before ME/CFS, Nicky was always on the […]

Patients Are the Heart of Our Mission—Every Discovery Starts with Their Voice

Wenzhong Xiao, headshot

At OMF Canada (OMFCA), there is no research without patients, no breakthrough without their voices, and no hope without their courage. Every study we fund, every collaboration we build, every scientific question we pursue begins and ends with one truth: patients are at the center of everything we do. Whether you live with ME/CFS or […]

Triple Giving November: 3x the impact, 3x the hope

OMF Canada (OMFCA)’s biggest fundraising event is here—Triple Giving November (TGN)! From November 1 to December 2, every donation will be TRIPLED, up to $500,000, thanks to generous matching donors. This makes TGN our most impactful time of the year—when your support can drive OMFCA’s research forward faster than ever. Why TGN Matters Tripling the […]

Coming soon: Triple Giving November and exclusive research updates

TGN logo: #TRIPLEGIVINGNOVEMBEROMFCA. The phrase is written in bold, uppercase letters with a mix of dark blue and light blue colors. The "OMFCA" text is in light blue, and there is a stylized heart shape in reddish-orange next to it.

This November, something special is returning — Triple Giving November (TGN)! Thanks to generous matching donors, every dollar you give to Open Medicine Foundation Canada (OMFCA) will be TRIPLED, up to $500,000. To make sure more people can take part in this opportunity, we’re extending Triple Giving November through December 2 — Giving Tuesday. That […]

POTS Awareness Day 2025

October is Dysautonomia Awareness Month and today, October 25th, we recognize POTS Awareness Day. Understanding Dysautonomia and POTS Dysautonomia is an umbrella term for a group of conditions that result from dysfunction of the autonomic nervous system (ANS)—the part of the nervous system that controls involuntary bodily functions, such as heart rate, blood pressure, breathing, […]

Maximize Your Impact on DAF Day – October 9, 2025

October 9 is DAF Day—a national day dedicated to the power of Donor-Advised Funds (DAFs) to make a difference. This year, you can multiply your impact by directing a grant from your DAF to Open Medicine Foundation Canada (OMFCA). To learn more about DAFs, visit our ways to donate page here.  Why give through your […]

New Publication from OMF Collaboration Investigates Molecular Basis of PEM

OMF’s Collaborative Center at Montreal, in collaboration with our Collaborative Center at Uppsala and the Computational Research Center for Complex Diseases, has released a new paper: Haptoglobin phenotypes and structural variants associate with post-exertional malaise and cognitive dysfunction in myalgic encephalomyelitis. From the Desk of Dr. Alain Moreau, Director of the ME/CFS Collaborative Research Center […]

New Publication from OMF Collaboration Investigates SMPDL3B Protein

OMF’s Collaborative Center at Montreal, in collaboration with our Melbourne ME/CFS Collaboration, has released a new paper: Circulating Levels of SMPDL3B Define Metabolic Endophenotypes and Subclinical Kidney Alterations in Myalgic Encephalomyelitis. From the Desk of Dr. Alain Moreau, Director of the ME/CFS Collaborative Research Center at Montreal: What is this research about? This study looked […]

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Microvesicles and viral sequencing
Microvesicles are a type of extracellular vesicle that is released from the cell membrane. Vesicles are small, fluid-filled sacs or vacuoles within the body. Sequencing is a technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA (or viral) molecule.
NMR Metabolomics
NMR (Nuclear Magnetic Resonance) is an instrument/tool used to perform metabolic studies, metabolic profiling, and metabolomics in biofluids and tissues for more than 40 years using magnetic fields. There is a very close connection between metabolic measurements and NMR. This connection has flourished because of NMR’s many unique strengths for characterizing complex mixtures’ chemical composition.
Proteomics
The large-scale study of proteins, which are large, complex molecules that are required for structure, function, and regulation of the human body's tissues and organs.
Autoantibodies
Antibodies that react with self-molecules and that occur in healthy individuals and are referred to as natural antibodies or autoantibodies.
Extracellular DNA for viral reactivation and Mitochondrial DNA
exDNA (extracellular DNA), exDNA is often secreted actively and is used to perform several tasks, thereby offering an attractive target or tool for biotechnological, medical, environmental, and general microbiological applications. Viruses are intracellular parasites that rely to a significant extent on the host cell for replication. Viral reactivation occurs when an active replication of the viral genome results in a lytic (degradation of the cell) infection characterized by the release of new progeny (descendant) virus particles.
Immune cell profiling
The immune system has many important regulatory roles in disease development and progression. Given the emergence of effective immune therapies, reliable predictors of response are needed. Immune cell profiling determines response by evaluating immune cell populations from treated and untreated samples. For our purposes, we will evaluate the white blood cell response to the viral infection using a process called “Cytof.”
Leukocyte Genomics
A leukocyte is a colorless cell circulating in the blood and body fluids and is involved in counteracting foreign substances and disease. A genome is all genetic material of an organism. Genomics is a biology field focusing on the structure, function, evolution, mapping, and editing of genomes. Therefore, leukocyte genomics is the study of all genetic material of leukocytes.
Metabolomics
Metabolomics is a way to study metabolism – that is, through measuring amounts of the metabolites (small molecules) produced by our bodies as we convert food into energy and other molecules that our cells need to survive. Metabolomics technology is ‘large-scale,’ meaning that several thousand metabolites can be measured from a single sample of e.g., blood or urine.
Micro RNA
Cells use Micro RNA to control whether a particular gene is making too much, too little or the normal amount of its protein at a particular time.