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Category: News

Announcing our sixth Research Center!

Triple Giving Tuesday starts today: Announcing our sixth Research Center! From the desk of Linda Tannenbaum Chief Executive Officer, Open Medicine Foundation Open Medicine Foundation Canada (OMFCA) is pleased to share, on the first day of our Triple Giving Tuesday campaign, some exciting research news! As part of our mission to fund and facilitate urgent, […]

New novel features main character with ME/CFS! ​📖

New novel features main character with ME/CFS! Spotlight on author Jean Meltzer, person with ME Author Jean Meltzer has the distinction of being an Emmy-award winning writer who is living with chronic illness and disability. Through her unique experiences, Jean is able to create diverse work that gives a voice to underrepresented communities. Open Medicine […]

Calling All Artists! 🎨

Calling all artists! Submit your art for a chance to become OMF’s Featured Artist during #TripleGivingTuesday! Are you an artist affected by chronic illness? Submit your artwork for a chance to become OMF & OMFCA’s Featured Artist for this year’s annual Triple Giving Tuesday campaign, our biggest fundraising event of the year! OMF & OMFCA welcomes the […]

Your powerful stories: #TheViewforME Gallery

Your Powerful Stories: #TheViewforME Gallery On August 8, Severe Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Awareness Day, Open Medicine Foundation Canada asked our community to share photos and short bios that capture the reality of life with this complex and devastating disease. Persons with severe ME/CFS are often so ill that they are bedbound for 24 […]

Planting seeds of hope: A mother’s plant sale benefits research

Today we share the story of a mother and daughter in Canada, the power of family, and their efforts to support critical research into ME/CFS. In 2017, Rebecca’s life was turned upside down when she came down with an illness that prevented her from leaving her bed and going to work. Soon after, she was […]

Last day to give to #MayMomentum!

Last day to give to #MayMomentum! There’s still time to make an impact and accelerate research around the globe —  donate to OMFCA’s May Momentum campaign today!   All gifts of any amount support urgent biomedical research to find treatments and a cure for millions suffering from ME/CFS and related complex diseases such as Post Treatment […]

ME/CFS Research Data: the heart of the matter

Wenzhong Xiao, headshot

ME/CFS Research Data: the heart of the matter With your support, Open Medicine Foundation funds open, collaborative research so that, as soon as possible, precise diagnostic tools and life-changing treatments can be available to people with ME/CFS and related chronic, complex diseases such as Post-Treatment Lyme Disease Syndrome, Fibromyalgia, and Post-COVID Syndrome. Each OMF funded […]

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Microvesicles and viral sequencing
Microvesicles are a type of extracellular vesicle that is released from the cell membrane. Vesicles are small, fluid-filled sacs or vacuoles within the body. Sequencing is a technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA (or viral) molecule.
NMR Metabolomics
NMR (Nuclear Magnetic Resonance) is an instrument/tool used to perform metabolic studies, metabolic profiling, and metabolomics in biofluids and tissues for more than 40 years using magnetic fields. There is a very close connection between metabolic measurements and NMR. This connection has flourished because of NMR’s many unique strengths for characterizing complex mixtures’ chemical composition.
Proteomics
The large-scale study of proteins, which are large, complex molecules that are required for structure, function, and regulation of the human body's tissues and organs.
Autoantibodies
Antibodies that react with self-molecules and that occur in healthy individuals and are referred to as natural antibodies or autoantibodies.
Extracellular DNA for viral reactivation and Mitochondrial DNA
exDNA (extracellular DNA), exDNA is often secreted actively and is used to perform several tasks, thereby offering an attractive target or tool for biotechnological, medical, environmental, and general microbiological applications. Viruses are intracellular parasites that rely to a significant extent on the host cell for replication. Viral reactivation occurs when an active replication of the viral genome results in a lytic (degradation of the cell) infection characterized by the release of new progeny (descendant) virus particles.
Immune cell profiling
The immune system has many important regulatory roles in disease development and progression. Given the emergence of effective immune therapies, reliable predictors of response are needed. Immune cell profiling determines response by evaluating immune cell populations from treated and untreated samples. For our purposes, we will evaluate the white blood cell response to the viral infection using a process called “Cytof.”
Leukocyte Genomics
A leukocyte is a colorless cell circulating in the blood and body fluids and is involved in counteracting foreign substances and disease. A genome is all genetic material of an organism. Genomics is a biology field focusing on the structure, function, evolution, mapping, and editing of genomes. Therefore, leukocyte genomics is the study of all genetic material of leukocytes.
Metabolomics
Metabolomics is a way to study metabolism – that is, through measuring amounts of the metabolites (small molecules) produced by our bodies as we convert food into energy and other molecules that our cells need to survive. Metabolomics technology is ‘large-scale,’ meaning that several thousand metabolites can be measured from a single sample of e.g., blood or urine.
Micro RNA
Cells use Micro RNA to control whether a particular gene is making too much, too little or the normal amount of its protein at a particular time.