Announcing OMF's First ME/CFS Clinical Trial!

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Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS) Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia Leading Research. Delivering Hope.Open Medicine Foundation® Canada

Driving research of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS),
Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia and Long COVID.

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Do you know how to accelerate finding a treatment?

Triple Giving Tuesday Launches Next Week!

It’s almost time to triple your impact to help find effective treatments. Mark your calendars! Open Medicine Foundation Canada (OMFCA)’s annual #TRIPLEGIVINGTUESDAY campaign launches next week! From November 1 through International Giving Tuesday on November 29, you will have the special opportunity to have your donation TRIPLED thanks to generous OMF donors who have agreed to match all donations up to $500,000. 

This year, Open Medicine Foundation’s focus is searching for effective treatments and we need your help!  Ahead of #TripleGivingTuesday (Nov 1), we’re sharing ways you can plan ahead to help accelerate research to find a treatment:

  • Starting November 1, launch your own triple match fundraiser! Check out our digital fundraising toolkit to kick off your fundraiser in 60 seconds or less, and tips and tricks for success. (Be sure to let your followers know, all donations to your fundraiser will be tripled!)
  • Donate any day of the week starting November 1! Help us get off to a great start – we’re hoping to break records this year as we fundraise for small clinical treatment trials.
  • Giving Stock. Do you own appreciated stocks? Stock gifts are a great opportunity to support OMF because your gift is mutually beneficial — we receive the full value of the stock, while you avoid paying capital gains tax! Learn more.
  • Include OMFCA in your will. Making a planned gift is an affordable way to make sure your legacy and OMF’s impact continue well into the future. Learn more.
  • Spread the word! Encourage your friends and family to join you in creating real impact throughout November by sharing what our mission means to you and why you support our organization (here are some ideas). Make sure to use hashtag #TripleGivingTuesday2022 and tag us so we can share!
  • Sharing is caring! Be sure to follow us on Instagram, Twitter, and Facebook and re-share our TripleGivingTuesday posts! 

 

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Microvesicles and viral sequencing
Microvesicles are a type of extracellular vesicle that is released from the cell membrane. Vesicles are small, fluid-filled sacs or vacuoles within the body. Sequencing is a technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA (or viral) molecule.
NMR Metabolomics
NMR (Nuclear Magnetic Resonance) is an instrument/tool used to perform metabolic studies, metabolic profiling, and metabolomics in biofluids and tissues for more than 40 years using magnetic fields. There is a very close connection between metabolic measurements and NMR. This connection has flourished because of NMR’s many unique strengths for characterizing complex mixtures’ chemical composition.
Proteomics
The large-scale study of proteins, which are large, complex molecules that are required for structure, function, and regulation of the human body's tissues and organs.
Immune cell profiling
The immune system has many important regulatory roles in disease development and progression. Given the emergence of effective immune therapies, reliable predictors of response are needed. Immune cell profiling determines response by evaluating immune cell populations from treated and untreated samples. For our purposes, we will evaluate the white blood cell response to the viral infection using a process called “Cytof.”
Leukocyte Genomics
A leukocyte is a colorless cell circulating in the blood and body fluids and is involved in counteracting foreign substances and disease. A genome is all genetic material of an organism. Genomics is a biology field focusing on the structure, function, evolution, mapping, and editing of genomes. Therefore, leukocyte genomics is the study of all genetic material of leukocytes.
Metabolomics
Metabolomics is a way to study metabolism – that is, through measuring amounts of the metabolites (small molecules) produced by our bodies as we convert food into energy and other molecules that our cells need to survive. Metabolomics technology is ‘large-scale,’ meaning that several thousand metabolites can be measured from a single sample of e.g., blood or urine.
Micro RNA
Cells use Micro RNA to control whether a particular gene is making too much, too little or the normal amount of its protein at a particular time.
Autoantibodies
Antibodies that react with self-molecules and that occur in healthy individuals and are referred to as natural antibodies or autoantibodies.
Extracellular DNA for viral reactivation and Mitochondrial DNA
exDNA (extracellular DNA), exDNA is often secreted actively and is used to perform several tasks, thereby offering an attractive target or tool for biotechnological, medical, environmental, and general microbiological applications. Viruses are intracellular parasites that rely to a significant extent on the host cell for replication. Viral reactivation occurs when an active replication of the viral genome results in a lytic (degradation of the cell) infection characterized by the release of new progeny (descendant) virus particles.