Announcing OMF's First ME/CFS Clinical Trial!

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Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS) Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia Leading Research. Delivering Hope.Open Medicine Foundation® Canada

Driving research of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS),
Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia and Long COVID.

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New interview with Ron Davis, PhD – and LAST DAY to give to May Momentum!

The Clock is Ticking!

Today is the LAST DAY to Give to May Momentum

May Momentum — our annual campaign to raise funds for research into ME/CFS and related multi-system chronic complex diseases (msCCD) — ends TODAY, Tuesday, May 31. We need your help now more than ever to fulfill our mission of finding effective treatments and improving overall healthcare for the millions who face these diseases every day. Each gift, large and small, makes a difference.

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New Interview with Ron Davis, PhD!

Today we are delighted to end our campaign by sharing a new interview with Ronald W. Davis, PhD. In this interview, Dr. Davis shares how he and his team at Stanford are working on developing innovative, low-cost technology in search of biomarkers and a cure.  

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Ensure that the momentum continues long after #MayMomentum ends by becoming a monthly donor! Your sustaining gift helps fund OMF’s top research talent, cutting-edge technologies, medical education initiatives, and more.

 

Thank you for your support and for being a part of our global OMFCA Family. 
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ICYMI: Want to Get Caught Up on OMF Funded Research?
Check Out Our May Momentum Tuesdays Webcast!  

May Momentum Tuesdays is a special effort to update the community on the progress of the OMF supported Collaborative Research Centers (CRC)s.

Click here to view all interviews with the six CRC Directors! (Be sure to turn on YouTube’s closed captions to view with subtitles.) We hope you find this series to be both informative and hopeful. Thank you to all who have tuned in!

 

 

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Microvesicles and viral sequencing
Microvesicles are a type of extracellular vesicle that is released from the cell membrane. Vesicles are small, fluid-filled sacs or vacuoles within the body. Sequencing is a technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA (or viral) molecule.
NMR Metabolomics
NMR (Nuclear Magnetic Resonance) is an instrument/tool used to perform metabolic studies, metabolic profiling, and metabolomics in biofluids and tissues for more than 40 years using magnetic fields. There is a very close connection between metabolic measurements and NMR. This connection has flourished because of NMR’s many unique strengths for characterizing complex mixtures’ chemical composition.
Proteomics
The large-scale study of proteins, which are large, complex molecules that are required for structure, function, and regulation of the human body's tissues and organs.
Immune cell profiling
The immune system has many important regulatory roles in disease development and progression. Given the emergence of effective immune therapies, reliable predictors of response are needed. Immune cell profiling determines response by evaluating immune cell populations from treated and untreated samples. For our purposes, we will evaluate the white blood cell response to the viral infection using a process called “Cytof.”
Leukocyte Genomics
A leukocyte is a colorless cell circulating in the blood and body fluids and is involved in counteracting foreign substances and disease. A genome is all genetic material of an organism. Genomics is a biology field focusing on the structure, function, evolution, mapping, and editing of genomes. Therefore, leukocyte genomics is the study of all genetic material of leukocytes.
Metabolomics
Metabolomics is a way to study metabolism – that is, through measuring amounts of the metabolites (small molecules) produced by our bodies as we convert food into energy and other molecules that our cells need to survive. Metabolomics technology is ‘large-scale,’ meaning that several thousand metabolites can be measured from a single sample of e.g., blood or urine.
Micro RNA
Cells use Micro RNA to control whether a particular gene is making too much, too little or the normal amount of its protein at a particular time.
Autoantibodies
Antibodies that react with self-molecules and that occur in healthy individuals and are referred to as natural antibodies or autoantibodies.
Extracellular DNA for viral reactivation and Mitochondrial DNA
exDNA (extracellular DNA), exDNA is often secreted actively and is used to perform several tasks, thereby offering an attractive target or tool for biotechnological, medical, environmental, and general microbiological applications. Viruses are intracellular parasites that rely to a significant extent on the host cell for replication. Viral reactivation occurs when an active replication of the viral genome results in a lytic (degradation of the cell) infection characterized by the release of new progeny (descendant) virus particles.