To explore the hypothesis that deranged flow of the cerebrospinal fluid (CSF) due to craniocervical obstructions and/or instability may cause deranged intracranial pressure (ICP), neuroinflammation and cardinal symptoms of ME/CFS.
Our study will be the first to systematically measure CNS structural abnormalities in a large ME/CFS case-control study using gold-standard methods. It will Highlight CSF pressure, structural abnormalities, and neuroinflammation, with pathophysiological implementations in ME/CFS. Added to this will be collected biospecimens to perform extensive state-of-the art analyses with the ambition to identify diagnostic and prognostic biomarkers
The IRB review will kick off shortly.
The overall aim is to explore the hypothesis that deranged flow of the cerebrospinal fluid (CSF) due to craniocervical obstructions and/or instability may cause deranged intracranial pressure (ICP), neuroinflammation and cardinal symptoms of ME/CFS. If this hypothesis proves true it opens a new research area in ME/CFS and hopes for effective treatment to regulate ICP and relieve symptoms associated with ME/CFS. This study will make use of CNS imaging and analysis of CSF, blood, saliva samples, and will identify proteomic and metabolomic biomarkers of the disease, a highly needed tool in the diagnostic and prognostic process. By the combination of more detailed clinical examination and evaluation and multiOmics biomarker analysis we will be able to provide a more individually adapted care and hopefully cure.
Donate your appreciated stock directly to OMFCA and you can receive an immediate income-tax deduction for the fair market value of the securities on the date of transfer (even if you originally paid much less for them).
OMFCA sells your securities and uses the proceeds to support our mission. You also do not pay capital gains tax on the transfer when the stock is sold. Giving appreciated stock can be more beneficial than giving cash. The “cost” of your gift is often less than the deduction you gain by making it. In advance, thank you for making this generous gift.
Gifting of Stock Instructions
Brokerage/Investment Firm: TD Waterhouse
Name on the Account: Open Medicine Foundation Canada
Account Number: 20LRHLA
OMFCA Canadian Revenue Agency (CRA) charity registration #: 74926 5518 RR0001
OMF Canada Registered Address:
Open Medicine Foundation Canada
2987 Baynes Road, Victoria, BC V8N-1Y4
Phone Number: 416-848-0055
Please speak to your personal tax advisor and then call OMFCA at 650-242-8669 to notify us of your donation or with any questions.