STUDY HYPOTHESIS AND DESCRIPTION
ME/CFS is diagnosed by its symptoms, which include post-exertional malaise, fatigue, and brain fog. It is unclear how these symptoms arise, and there are likely multiple routes to arrive at this chronic pathological state. However, there is a fundamental defect in energy metabolism in ME/CFS, which may be a common underlying cause of its symptoms.
We have hypothesized that reactive nitrogen by-products are accumulating in the cells of ME/CFS patients as a result of using amino acids for energy production in the mitochondria.To test this hypothesis, we will culture blood-based immune cells and feed them with labelled sugar, fats and amino acids. As the cells use the labelled sugar, fatand amino acids for energy production we will be able to monitor how their metabolism differs from healthy controls.
Donate your appreciated stock directly to OMFCA and you can receive an immediate income-tax deduction for the fair market value of the securities on the date of transfer (even if you originally paid much less for them).
OMFCA sells your securities and uses the proceeds to support our mission. You also do not pay capital gains tax on the transfer when the stock is sold. Giving appreciated stock can be more beneficial than giving cash. The “cost” of your gift is often less than the deduction you gain by making it. In advance, thank you for making this generous gift.
Gifting of Stock Instructions
Brokerage/Investment Firm: TD Waterhouse
Name on the Account: Open Medicine Foundation Canada
Account Number: 20LRHLA
OMFCA Canadian Revenue Agency (CRA) charity registration #: 74926 5518 RR0001
OMF Canada Registered Address:
Open Medicine Foundation Canada
2987 Baynes Road, Victoria, BC V8N-1Y4
Phone Number: 416-848-0055
Please speak to your personal tax advisor and then call OMFCA at 650-242-8669 to notify us of your donation or with any questions.