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Category: News

Exciting News: Harvard Collaborative Projects Advancing

#TripleTuesdayOMFCA Spotlight – Harvard Collaboration Every donation today through December 3 will be tripled! The OMF funded Harvard ME/CFS Collaboration, led by Ronald G. Tompkins, MD, ScD, and Wenzhong Xiao, PhD, is a partnership of leading scientists, doctors, and researchers from Harvard-affiliated hospitals including Massachusetts General Hospital (MGH) and collaborators from Sweden and the United […]

TRIPLE GIVING TUESDAY OMF CANADA LAUNCHES

Every donation today through December 3 will be tripled! Today is the first day of Triple Giving Tuesday fundraising campaign, and I’m excited to announce that we have secured matching gifts up to $200 000 through the generosity of several supporters. Thanks to these individuals, when you donate to OMFCA any day of the week today […]

NEW GUIDELINES FOR DIAGNOSING AND TREATING ME/CFS

A resource for clinicians and patients. The U.S. ME/CFS Clinician Coalition, a group of U.S. ME/CFS experts, has authored a handout on the basics of diagnosis and management of ME/CFS. This handout is being made available on our website for the medical community to help them better understand how to recognize ME/CFS and how to […]

Red Blood Cell Deformability is diminished in patients with Chronic Fatigue Syndrome, by Anand Ramasubramanian, PhD and Ronald Davis, PhD, Stanford Collaboration

As promised, below is the link to the complete version of the Red Blood Cell (RBC) Deformability research paper, which has now been formally published, open source, in Clinical Hemorheology and Microcirculation. The authors are Mohsen Nemat-Gorgani, PhD, of Stanford University, and Anand Ramasubramanian, PhD, of San Jose State University, in collaboration with Ron Davis, PhD, and their teams. This important […]

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Microvesicles and viral sequencing
Microvesicles are a type of extracellular vesicle that is released from the cell membrane. Vesicles are small, fluid-filled sacs or vacuoles within the body. Sequencing is a technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA (or viral) molecule.
NMR Metabolomics
NMR (Nuclear Magnetic Resonance) is an instrument/tool used to perform metabolic studies, metabolic profiling, and metabolomics in biofluids and tissues for more than 40 years using magnetic fields. There is a very close connection between metabolic measurements and NMR. This connection has flourished because of NMR’s many unique strengths for characterizing complex mixtures’ chemical composition.
Proteomics
The large-scale study of proteins, which are large, complex molecules that are required for structure, function, and regulation of the human body's tissues and organs.
Autoantibodies
Antibodies that react with self-molecules and that occur in healthy individuals and are referred to as natural antibodies or autoantibodies.
Extracellular DNA for viral reactivation and Mitochondrial DNA
exDNA (extracellular DNA), exDNA is often secreted actively and is used to perform several tasks, thereby offering an attractive target or tool for biotechnological, medical, environmental, and general microbiological applications. Viruses are intracellular parasites that rely to a significant extent on the host cell for replication. Viral reactivation occurs when an active replication of the viral genome results in a lytic (degradation of the cell) infection characterized by the release of new progeny (descendant) virus particles.
Immune cell profiling
The immune system has many important regulatory roles in disease development and progression. Given the emergence of effective immune therapies, reliable predictors of response are needed. Immune cell profiling determines response by evaluating immune cell populations from treated and untreated samples. For our purposes, we will evaluate the white blood cell response to the viral infection using a process called “Cytof.”
Leukocyte Genomics
A leukocyte is a colorless cell circulating in the blood and body fluids and is involved in counteracting foreign substances and disease. A genome is all genetic material of an organism. Genomics is a biology field focusing on the structure, function, evolution, mapping, and editing of genomes. Therefore, leukocyte genomics is the study of all genetic material of leukocytes.
Metabolomics
Metabolomics is a way to study metabolism – that is, through measuring amounts of the metabolites (small molecules) produced by our bodies as we convert food into energy and other molecules that our cells need to survive. Metabolomics technology is ‘large-scale,’ meaning that several thousand metabolites can be measured from a single sample of e.g., blood or urine.
Micro RNA
Cells use Micro RNA to control whether a particular gene is making too much, too little or the normal amount of its protein at a particular time.