Update: Patient-Reported Treatment Outcomes in ME/CFS and Long COVID

From the Desk of Dr. Danielle MeadowsVice President of Research Programs & Operations In the past, I’ve shared some information about the peer-review publication process—the last stage of the research process—and the concept of a preprint. We recognize that the publication process takes a long time, and we want to provide results and helpful information […]

🧬Science Wednesdays: What is an IRB or Ethics Board?

Two healthcare professionals are reviewing a document on a clipboard. One is wearing teal scrubs, and the other is in a white lab coat over blue scrubs with a stethoscope visible around their neck.

What is an IRB or Ethics Board? From the Desk of Dr. Danielle MeadowsVice President of Research Programs & Operations The IRB plays a central role in the first stage of the research process—linked here again if you missed it—so it’s probably about time I talk about what an IRB (or the non-US equivalent) actually is […]

Update: A Muscle Biopsy Study to Understand the Molecular Mechanisms of PEM

From the Desk of Dr. Danielle MeadowsVice President of Research Programs & Operations Today, I’m happy to share another update on a study that I introduced back in November 2024 in an interview with Dr. Systrom. The study is still going on, but in this case, we’re able to share some exciting preliminary data. We […]

An Update from Dr. Chris Armstrong: The Science Behind Hope

Today, we’re sharing an update on important developments in ME/CFS research — work that is steadily improving our understanding of the biology behind this complex and often life-altering condition. Whether a person’s ME/CFS began decades ago or more recently, the challenges are real and often devastating. Our research is focused on uncovering the underlying mechanisms […]

Update: MRI and PET Imaging of ME/CFS, POTS, and Long COVID

From the Desk of Dr. Danielle Meadows, Vice President of Research Programs & Operations In the fall of 2024, I introduced to you all an overview of the research process, where studies typically move through four main stages: Study Design, IRB/Ethics Review; Recruitment, Data Collection; Data Analysis; and Publication.  Given that context, I then shared […]

OMF CRCs Directors Meet in Person to Advance Research

In May, I had the privilege of attending the 2025 Invest in ME Research International Conference in Cambridge, UK, along with OMF’s research Directors. This annual event brings together scientists, clinicians, and advocates committed to advancing ME/CFS and Long COVID research worldwide. Following the conference, OMF’s CRC Directors gathered for an additional two-day, in-person meeting. […]

🧬Science Wednesdays: Statistics 101

This image is a conceptual representation of statistics and data analysis. It features a group of professionals collaborating at a desk with a city skyline illuminated at night. Overlaid on the image are various graphical elements associated with data, such as bar charts, radar charts, pie charts, and data points.

Statistics 101 From the Desk of Dr. Danielle Meadows Vice President of Research Programs & Operations A few months ago, I started talking about evaluating research studies by going through what it means to be a well-powered study. As part of that discussion (you can read it here if you missed it), I mentioned statistical […]

New Publication from the OMF’s Collaborative Center at Uppsala

We’re pleased to share a new publication by Jonas Bergquist, MD, PhD, and colleagues: “Comprehensive transcriptome assessment in PBMC of post-COVID patients at two years after a mild COVID infection reveals upregulation of JAK/STAT signaling and chronic inflammation.” The Heart of the Matter The Director of OMF’s Collaborative Center at Uppsala, Dr. Jonas Bergquist, recently published […]

Myalgic Encephalomyelitis Adaptive Therapeutic Solution Platform (MEDUSA)

From the Desk of Dr. Danielle MeadowsVice President of Research Programs & Operations The four major stages of the research process that I’ve laid out in previous messages are generally applicable to any given clinical research study. But sometimes, this process can be almost cyclical rather than standalone, which is the case for the new […]

Research Update: Refining a Diagnostic Model and Designing a New PEM Project

May Momentum logo- You are the motivation behind our momentum

As part of our May Momentum campaign, we are excited to share an interview with Chris Armstrong, PhD, and post-doctoral researcher, Kathy Huang, PhD, about their ongoing ME/CFS research. Please consider making a donation today to support our ongoing research efforts and bring us closer to finding effective diagnostics and treatments for millions worldwide. Every contribution, […]