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Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS) Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia Leading Research. Delivering Hope.Open Medicine Foundation® Canada
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ME/CFS Collaborative
Research Center

at the CHU Sainte-Justine/
Université de Montréal

Clinical and scientific studies to understand and discover new treatments for Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS)
Science Team
Research

About the research center

The ME / CFS Collaborative Research Center, established in 2020 at CHU Sainte-Justine /Université de Montréal, increases OMF’s international collaborative efforts through the End ME/CFS Project. Directed by Alain Moreau, PhD, the Quebec, Canada-based laboratory has been researching ME / CFS for several years.

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Alain Moreau, portrait Alain Moreau, PhD, is a Full Professor in the Department of Stomatology, Faculty of Dentistry and Department of Biochemistry and Molecular Medicine, Faculty of Medicine, at Université de Montréal, Montréal, Québec, Canada. Additionally, Dr. Moreau is the Director of Network for Canadian Oral Health Research. He is the Scientific Director of the Viscogliosi Laboratory in Molecular Genetics of Musculoskeletal Diseases, Sainte-Justine University Research Center, Montréal, Québec.

Dr. Moreau’s chief interests of study are pediatric scoliosis, osteoarthritis, osteoporosis, and Myalgic Encephalomyelitis. Dr. Moreau is a member of the Open Medicine Foundation Scientific Advisory Board and is the Director of the Interdisciplinary Canadian Collaborative Myalgic Encephalomyelitis Research Network, a national research network funded by the Canadian Institute of Health Research. 

Active/Ongoing studies

Inactive/Archived Studies

Scientific Team

chercheuse regardant de près des échantillons

CHU Sainte-Justine Research Center
Université de Montréal

Alain Moreau, PhD , Scientific Director

Anita Franco, MSc, Lab coordinator

Dashen Wang, MD, PhD, Research Associate

Mohamed Elbakry, PhD , Research Associate

Viorica Lascau, MSc , Research coordinator – certification manager

Sophie Perreault, RN  , Clinical research nurse

Valerie Tremblay, RN, Clinical research nurse

Hélène Gagnon, RN, Clinical research nurse

Iurie Caraus, PhD , Postdoctoral fellow

Wesam Elremaly, PhD, Postdoctoral fellow

Lynda Chalder, MSc, PhD student

Evguenia Nepotchatykh, BSc, PhD student

Atefeh Moezzi, MSc, PhD student

Corinne Leveau, BSc, MSc student

Bita Rostami, BSc, MSc student

Marie-Yvonne Akoume PhD, Invited professor – ICanCME Research Network Investigator

Valérie Marcil PhD, Associate Professor – ICanCME Research Network Investigator

Emile Levy, MD, PhD ,Full Professor – ICanCME Research Network Investigator

University of Florida Atlantic

Dawei Li, PhD, Associated Professor – ICanCME Research Network Investigator

Jason Kost BSc , Research Assistant – ICanCME Research Network Member

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Learn about Our Other OMF Funded Collaborative Research Centers

Stanford
Harvard
Uppsala
Melbourne

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Data Subject Access Request (DSAR) Form 

Microvesicles and viral sequencing
Microvesicles are a type of extracellular vesicle that is released from the cell membrane. Vesicles are small, fluid-filled sacs or vacuoles within the body. Sequencing is a technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA (or viral) molecule.
NMR Metabolomics
NMR (Nuclear Magnetic Resonance) is an instrument/tool used to perform metabolic studies, metabolic profiling, and metabolomics in biofluids and tissues for more than 40 years using magnetic fields. There is a very close connection between metabolic measurements and NMR. This connection has flourished because of NMR’s many unique strengths for characterizing complex mixtures’ chemical composition.
Proteomics
The large-scale study of proteins, which are large, complex molecules that are required for structure, function, and regulation of the human body's tissues and organs.
Autoantibodies
Antibodies that react with self-molecules and that occur in healthy individuals and are referred to as natural antibodies or autoantibodies.
Extracellular DNA for viral reactivation and Mitochondrial DNA
exDNA (extracellular DNA), exDNA is often secreted actively and is used to perform several tasks, thereby offering an attractive target or tool for biotechnological, medical, environmental, and general microbiological applications. Viruses are intracellular parasites that rely to a significant extent on the host cell for replication. Viral reactivation occurs when an active replication of the viral genome results in a lytic (degradation of the cell) infection characterized by the release of new progeny (descendant) virus particles.
Immune cell profiling
The immune system has many important regulatory roles in disease development and progression. Given the emergence of effective immune therapies, reliable predictors of response are needed. Immune cell profiling determines response by evaluating immune cell populations from treated and untreated samples. For our purposes, we will evaluate the white blood cell response to the viral infection using a process called “Cytof.”
Leukocyte Genomics
A leukocyte is a colorless cell circulating in the blood and body fluids and is involved in counteracting foreign substances and disease. A genome is all genetic material of an organism. Genomics is a biology field focusing on the structure, function, evolution, mapping, and editing of genomes. Therefore, leukocyte genomics is the study of all genetic material of leukocytes.
Metabolomics
Metabolomics is a way to study metabolism – that is, through measuring amounts of the metabolites (small molecules) produced by our bodies as we convert food into energy and other molecules that our cells need to survive. Metabolomics technology is ‘large-scale,’ meaning that several thousand metabolites can be measured from a single sample of e.g., blood or urine.
Micro RNA
Cells use Micro RNA to control whether a particular gene is making too much, too little or the normal amount of its protein at a particular time.