Neuro Inflammation
This study is designed to explore the hypothesis that deranged flow of the cerebrospinal fluid (CSF) due to craniocervical obstructions and/or instability may cause deranged intracranial pressure (ICP), neuroinflammation and cardinal symptoms of ME/CFS.
Multi-omics
Autoimmunity and Autoantibodies
The aim is to investigate potential differences in adrenergic and muscarinic receptor autoantibody levels in plasma and cerebrospinal fluid samples between ME/CFS patients and healthy controls.
Post-viral Encephalopathy
This study provides an excellent opportunity to understand the mechanism of long-lasting viral-induced cognitive complications, commonly referred to as “brain fog.”
Mestinon Clinical Trial
This clinical trial will test the exercise response to Mestinon in people with ME/CFS.
Nanoneedle Diagnostic Tool
The technology will be optimized for easy clinical adoption and scaled up so that numerous FDA-approved drugs can be simultaneously screened as potential treatments.
Metabolic Trap Study
The aim of this study was to test the hypothesis developed by Dr. Phair that a crucial component of metabolism in ME/CFS patients appears to be “trapped” in an unhealthy state.
Severely iIl Patient
The goal of the Severely ill Patient Study was to conduct a comprehensive “Big Data” analysis on severely ill ME/CFS patients in order to begin an exploration to find the molecular basis of ME/CFS.
T cells and Immunology
The study’s objective was to establish the role of T cells and the immune system in ME/CFS by examining the genetic material in T cells — immune cells that identify and kill infected cells.
Extended Big Data Study in Families
The goal of this study was to extend the Severely ill Patient Study and conduct a comprehensive “Big Data” analysis on ME/CFS patients and their families.