Study of COVID-19 survivors’ profiles for detection of ME/CFS (SCOPIMED)
The purpose of this study is to capture a post-COVID-19 infected population willing to participate in phenotyping studies early in the post-COVID-19 illness progression, with an aim of providing targeted effective therapies and preventing the onset and progression of ME/CFS.
Multi-Omics Study of ME/CFS (MAESTRO)
The primary goal of this project is to complete our comprehensive analysis of the genome, methylome, miRnome, and their interactions in order to fill the gaps in our understanding of ME/CFS pathophysiology and to identify clinically useful biomarkers.
Precision Medicine for Myalgic Encephalomyelitis Drug Discovery and ClinicaI Trials (REMEDIAL)
The REMEDIAL project continues the work
commenced with MAESTRO and will lead to a
better understanding of the molecular
mechanisms underlying ME/CFS pathophysiology,
the persistence and variability of the symptoms,
and will contribute to the identification of targets
and therapeutic agents for intervention.
Stress-Activated MicroRNAs
Studying microRNAs could help to bridge the conceptual gap between genetic predisposition and environmental factors causing ME/CFS or exacerbating specific symptoms.
Critical Illness, Mechanisms of Recovery, Similarities to ME/CFS
We propose an initial explanation for how ME/CFS could originate and perpetuate by drawing on findings from critical illness and heat stroke research.
Studying CSF to further reveal pathogenesis mechanisms in ME/CFS
The goal of this research is to reveal more information about the role of immunology and neuroinflammation in ME/CFS, and the underlying mechanisms of related pathogenesis that takes place.
Long COVID Clinic Studies
Long COVID Clinic Studies Study AIM The newly established clinic in Uppsala will continue the work of the OMF-Funded MultiCenter Collaborative Study on COVID to ME/CFS progression. LEAD INVESTIGATORS Jonas Bergquist, MD, PhD, Prof, Director ScD Updates and Potential Studies A & B: IRB protocol has been approved, and patients are being recruited. STUDY […]
Home Visit Study
Home Visit Study STUDY AIM This study provides a unique opportunity to bring the lab directly into patient homes and provide immediate analysis of samples over an extended period of time. This longitudinal approach without the invasive and/or PEM-induced measures will be vitally important in other patient cohorts and will decrease the study impact on […]
Deep Proteome and Metabolome Profiling
Decode the molecular mechanisms underlying ME/CFS and contributing to specific symptoms with a particular emphasis of post-exertional malaise (PEM). This includes deep phenotyping of ME patients and global proteomic/metabolomics plasma profiling of ME..
