Stress-Activated MicroRNAs

Studying microRNAs could help to bridge the conceptual gap between genetic predisposition and environmental factors causing ME/CFS or exacerbating specific symptoms.

Long COVID Clinic Studies

Long COVID Clinic Studies Study AIM The newly established clinic in Uppsala will continue the work of the OMF-Funded MultiCenter Collaborative Study on COVID to ME/CFS progression. LEAD INVESTIGATORS Jonas Bergquist, MD, PhD, Prof, Director ScD Updates and Potential Studies A & B: IRB protocol has been approved, and patients are being recruited.   STUDY […]

Home Visit Study

Home Visit Study STUDY AIM This study provides a unique opportunity to bring the lab directly into patient homes and provide immediate analysis of samples over an extended period of time. This longitudinal approach without the invasive and/or PEM-induced measures will be vitally important in other patient cohorts and will decrease the study impact on […]

Deep Proteome and Metabolome Profiling

Deep Proteome and Metabolome Profiling Study AIM Collaborate with OMF CRCs in Uppsala and Melbourne to establish a global perspective. Decode the molecular mechanisms underlying ME/CFS and contributing to specific symptoms with a particular emphasis of post-exertional malaise (PEM) through:  Deep phenotyping of ME patients  Global proteomic plasma profiling of ME patients Global metabolomics plasma […]

Neuro Inflammation

Deep Assessment of NeuroinflammationUsing CNS Imaging and Analysis of CSF, Blood, Saliva Samples Study AIM To explore the hypothesis that deranged flow of the cerebrospinal fluid (CSF) due to craniocervical obstructions and/or instability may cause deranged intracranial pressure (ICP), neuroinflammation and cardinal symptoms of ME/CFS. LEAD INVESTIGATORS Jonas Bergquist in collaboration with the Haravard CRC […]