Multi-Omics Study of ME/CFS (MAESTRO)

The primary goal of this project is to complete our comprehensive analysis of the genome, methylome, miRnome, and their interactions in order to fill the gaps in our understanding of ME/CFS pathophysiology and to identify clinically useful biomarkers.

Stress-Activated MicroRNAs

Studying microRNAs could help to bridge the conceptual gap between genetic predisposition and environmental factors causing ME/CFS or exacerbating specific symptoms.

Long COVID Clinic Studies

Long COVID Clinic Studies Study AIM The newly established clinic in Uppsala will continue the work of the OMF-Funded MultiCenter Collaborative Study on COVID to ME/CFS progression. LEAD INVESTIGATORS Jonas Bergquist, MD, PhD, Prof, Director ScD Updates and Potential Studies A & B: IRB protocol has been approved, and patients are being recruited.   STUDY […]

Home Visit Study

Home Visit Study STUDY AIM This study provides a unique opportunity to bring the lab directly into patient homes and provide immediate analysis of samples over an extended period of time. This longitudinal approach without the invasive and/or PEM-induced measures will be vitally important in other patient cohorts and will decrease the study impact on […]

Deep Proteome and Metabolome Profiling

Decode the molecular mechanisms underlying ME/CFS and contributing to specific symptoms with a particular emphasis of post-exertional malaise (PEM). This includes deep phenotyping of ME patients and global proteomic/metabolomics plasma profiling of ME..