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Category: News

Supporting disabled artists: Exclusive interview with Jacqueline Ko!

#TripleGivingTuesday Ambassador Spotlight How Jacqueline Ko is “Holding Space” for artists with disabilities and chronic illnesses Multi-award-winning opera singer and Canadian OMF Ambassador Jacqueline Ko, long known for her critically acclaimed stage performances, is working urgently to promote inclusivity and accessibility within the opera industry and beyond.  We are honored to share the following interview […]

New Study Alert! Sleep Disturbances in ME/CFS

#TripleGivingTuesday news: New Study Underway! Sleep Disturbances in ME/CFS From the desk of Ronald Tompkins, MD, ScDDirector, ME/CFS Harvard CollaborationChief Medical Officer, Open Medicine Foundation To kick off the second week of Triple Giving Tuesday, Open Medicine Foundation Canada (OMFCA) is thrilled to announce that we are funding a new collaborative research project! Conducted across the […]

New study underway at the Montreal Collaborative Center!

#TripleGivingTuesday Research Feature New OMF funded study: Deep proteome and metabolome profiling From the desk of Alain Moreau, PhDDirector of the ME/CFS Collaborative Research Center at CHU Sainte-Justine/Université de Montréal During this first week of #TripleGivingTuesday, I am honored to share the exciting news that a new study is underway at the ME/CFS Collaborative Research […]

New Tool to Educate Your Community About Chronic Disease!

Introducing OMFCA’s Social Shareables Web Portal! New tool to help educate your personal communities As part of #TripleGivingTuesday, we are pleased to announce that we have developed a new tool to help you educate your personal communities about ME/CFS and related multisystem chronic, complex diseases (msCCD). Check out our new Social Shareables site now! Use […]

Biologists/bioinformaticians — Join our team at the Computational Research Center for Complex Diseases

We are looking for talented computational biologists/bioinformaticians to join the team at the Computational Research Center for Complex Diseases to discover the molecular mechanism and treatments for ME/CFS and related complex human diseases. Potential projects include: Working closely with researchers and clinicians at OMF supported Collaborative Research Centers to perform integrative analysis of multiple omics datasets (e.g., […]

Announcing our sixth Research Center!

Triple Giving Tuesday starts today: Announcing our sixth Research Center! From the desk of Linda Tannenbaum Chief Executive Officer, Open Medicine Foundation Open Medicine Foundation Canada (OMFCA) is pleased to share, on the first day of our Triple Giving Tuesday campaign, some exciting research news! As part of our mission to fund and facilitate urgent, […]

New novel features main character with ME/CFS! ​📖

New novel features main character with ME/CFS! Spotlight on author Jean Meltzer, person with ME Author Jean Meltzer has the distinction of being an Emmy-award winning writer who is living with chronic illness and disability. Through her unique experiences, Jean is able to create diverse work that gives a voice to underrepresented communities. Open Medicine […]

Calling All Artists! 🎨

Calling all artists! Submit your art for a chance to become OMF’s Featured Artist during #TripleGivingTuesday! Are you an artist affected by chronic illness? Submit your artwork for a chance to become OMF & OMFCA’s Featured Artist for this year’s annual Triple Giving Tuesday campaign, our biggest fundraising event of the year! OMF & OMFCA welcomes the […]

Your powerful stories: #TheViewforME Gallery

Your Powerful Stories: #TheViewforME Gallery On August 8, Severe Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Awareness Day, Open Medicine Foundation Canada asked our community to share photos and short bios that capture the reality of life with this complex and devastating disease. Persons with severe ME/CFS are often so ill that they are bedbound for 24 […]

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Microvesicles and viral sequencing
Microvesicles are a type of extracellular vesicle that is released from the cell membrane. Vesicles are small, fluid-filled sacs or vacuoles within the body. Sequencing is a technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA (or viral) molecule.
NMR Metabolomics
NMR (Nuclear Magnetic Resonance) is an instrument/tool used to perform metabolic studies, metabolic profiling, and metabolomics in biofluids and tissues for more than 40 years using magnetic fields. There is a very close connection between metabolic measurements and NMR. This connection has flourished because of NMR’s many unique strengths for characterizing complex mixtures’ chemical composition.
Proteomics
The large-scale study of proteins, which are large, complex molecules that are required for structure, function, and regulation of the human body's tissues and organs.
Autoantibodies
Antibodies that react with self-molecules and that occur in healthy individuals and are referred to as natural antibodies or autoantibodies.
Extracellular DNA for viral reactivation and Mitochondrial DNA
exDNA (extracellular DNA), exDNA is often secreted actively and is used to perform several tasks, thereby offering an attractive target or tool for biotechnological, medical, environmental, and general microbiological applications. Viruses are intracellular parasites that rely to a significant extent on the host cell for replication. Viral reactivation occurs when an active replication of the viral genome results in a lytic (degradation of the cell) infection characterized by the release of new progeny (descendant) virus particles.
Immune cell profiling
The immune system has many important regulatory roles in disease development and progression. Given the emergence of effective immune therapies, reliable predictors of response are needed. Immune cell profiling determines response by evaluating immune cell populations from treated and untreated samples. For our purposes, we will evaluate the white blood cell response to the viral infection using a process called “Cytof.”
Leukocyte Genomics
A leukocyte is a colorless cell circulating in the blood and body fluids and is involved in counteracting foreign substances and disease. A genome is all genetic material of an organism. Genomics is a biology field focusing on the structure, function, evolution, mapping, and editing of genomes. Therefore, leukocyte genomics is the study of all genetic material of leukocytes.
Metabolomics
Metabolomics is a way to study metabolism – that is, through measuring amounts of the metabolites (small molecules) produced by our bodies as we convert food into energy and other molecules that our cells need to survive. Metabolomics technology is ‘large-scale,’ meaning that several thousand metabolites can be measured from a single sample of e.g., blood or urine.
Micro RNA
Cells use Micro RNA to control whether a particular gene is making too much, too little or the normal amount of its protein at a particular time.