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Category: News

#TripleTuesdayOMFCA Spotlight – iCPET Study

Proteomic and Metabolic Plasma iCPET Studies By Ronald G.Tompkins, MD, ScD We have received an anonymous grant of $350,000 designated for the “Proteomic and Metabolomic Plasma iCPET Studies” within the OMFCA-funded Harvard ME / CFS Collaboration at the Harvard-Affiliated Hospitals. Dr. David Systrom and his colleagues at the Brigham and Women’s Hospital have developed a […]

Ron Davis talks ME / CFS at Columbia and Princeton

Written by Janet Dafoe, PhD   Ron Davis spent the last week on the East Coast giving talks and talking individually to scientists and doctors about Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS). First, he spent two days at Princeton University. He talked to individuals, groups of graduate students, and groups at lunches […]

How Patients Are Accelerating Research

I’m very grateful for the outpouring of support we’ve received from OMFCA community members, people just like you, during our Triple Giving Tuesday campaign. I’m especially inspired by the ME/CFS patients who dedicate their limited energy to fundraising for our work. I am honored to highlight a few of their stories today. First though, I’d […]

Experts advance ME/CFS research: Chris Armstrong interviewed on ME/CFS Alert

Dr. Christopher Armstrong Talks with Llewellyn King Llewellyn King, host of ME/CFS Alert, has just released his newest episode interviewing OMF Science Liaison Christopher Armstrong, PhD. This edition covers Dr. Armstrong’s pathway into ME/CFS research, his areas of expertise, and his role to help advance OMFCA’s ME/CFS research. This is the third in a series […]

ME/CFS Research is soaring!

#TripleTuesdayOMFCA Spotlight – Chris Armstrong, PhD Every donation today through December 3 will be tripled!   I’m getting in touch with you today to share my personal perspective on why your support is so vital to OMF Canada’s (OMFCA) work. Donations from community members like you allow OMFCA to fund critical research around the globe […]

Dr. Chris Armstrong Speaks Out About ME/CFS

Uninvisible Podcast Episode #46 OMF Science Liaison Christopher Armstrong, PhD, is the guest speaker on the latest episode of Uninvisible Podcast with host and chronic disease patient advocate, Lauren Freedman. The Uninvisible Podcast focuses on invisible conditions and invisible chronic illness. In this interview, Chris shared that OMFCA is focused on research to establish the biology […]

Exciting News: Harvard Collaborative Projects Advancing

#TripleTuesdayOMFCA Spotlight – Harvard Collaboration Every donation today through December 3 will be tripled! The OMF funded Harvard ME/CFS Collaboration, led by Ronald G. Tompkins, MD, ScD, and Wenzhong Xiao, PhD, is a partnership of leading scientists, doctors, and researchers from Harvard-affiliated hospitals including Massachusetts General Hospital (MGH) and collaborators from Sweden and the United […]

TRIPLE GIVING TUESDAY OMF CANADA LAUNCHES

Every donation today through December 3 will be tripled! Today is the first day of Triple Giving Tuesday fundraising campaign, and I’m excited to announce that we have secured matching gifts up to $200 000 through the generosity of several supporters. Thanks to these individuals, when you donate to OMFCA any day of the week today […]

University of Victoria Hosts Educational Seminar on ME/CFS

We’d like to say a special thanks today to Lauren Grubisich for helping to raise awareness of ME/CFS in Canada! Lauren is a Director at Large of The University of Victoria Society for Students with a Disability which recently partnered with the ME|FM Society of BC and The UVic Equity and Human Rights Office to […]

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Microvesicles and viral sequencing
Microvesicles are a type of extracellular vesicle that is released from the cell membrane. Vesicles are small, fluid-filled sacs or vacuoles within the body. Sequencing is a technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA (or viral) molecule.
NMR Metabolomics
NMR (Nuclear Magnetic Resonance) is an instrument/tool used to perform metabolic studies, metabolic profiling, and metabolomics in biofluids and tissues for more than 40 years using magnetic fields. There is a very close connection between metabolic measurements and NMR. This connection has flourished because of NMR’s many unique strengths for characterizing complex mixtures’ chemical composition.
Proteomics
The large-scale study of proteins, which are large, complex molecules that are required for structure, function, and regulation of the human body's tissues and organs.
Autoantibodies
Antibodies that react with self-molecules and that occur in healthy individuals and are referred to as natural antibodies or autoantibodies.
Extracellular DNA for viral reactivation and Mitochondrial DNA
exDNA (extracellular DNA), exDNA is often secreted actively and is used to perform several tasks, thereby offering an attractive target or tool for biotechnological, medical, environmental, and general microbiological applications. Viruses are intracellular parasites that rely to a significant extent on the host cell for replication. Viral reactivation occurs when an active replication of the viral genome results in a lytic (degradation of the cell) infection characterized by the release of new progeny (descendant) virus particles.
Immune cell profiling
The immune system has many important regulatory roles in disease development and progression. Given the emergence of effective immune therapies, reliable predictors of response are needed. Immune cell profiling determines response by evaluating immune cell populations from treated and untreated samples. For our purposes, we will evaluate the white blood cell response to the viral infection using a process called “Cytof.”
Leukocyte Genomics
A leukocyte is a colorless cell circulating in the blood and body fluids and is involved in counteracting foreign substances and disease. A genome is all genetic material of an organism. Genomics is a biology field focusing on the structure, function, evolution, mapping, and editing of genomes. Therefore, leukocyte genomics is the study of all genetic material of leukocytes.
Metabolomics
Metabolomics is a way to study metabolism – that is, through measuring amounts of the metabolites (small molecules) produced by our bodies as we convert food into energy and other molecules that our cells need to survive. Metabolomics technology is ‘large-scale,’ meaning that several thousand metabolites can be measured from a single sample of e.g., blood or urine.
Micro RNA
Cells use Micro RNA to control whether a particular gene is making too much, too little or the normal amount of its protein at a particular time.