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Category: News

Opera Singer Jacqueline Ko Becomes OMF Canada Ambassador

Join us to welcome Jacqueline and help raise awareness. We are excited to welcome Canadian opera singer, producer and disability advocate Jacqueline Ko as our new OMF Canada Ambassador! Despite her struggle with ME/CFS, which left her bedbound for years, Jacqueline has received multiple awards for her singing, and critical acclaim for her roles in […]

Individual Community Symposium Talks Now Available on OMF YouTube Channel

The individual talks from the OMF-sponsored Third Annual Community Symposium on the Molecular Basis of ME/CFS at Stanford University are now available as individual talks in a full playlist on OMF’s YouTube channel. Check out the speakers you are interested in hearing from, the panel discussions where they answer questions from our worldwide audience, or watch the […]

Linda Tannenbaum & Llewellyn King Interviewed on Joe Madison

OMF CA Founder & President Linda Tannenbaum and activist, reporter, and OMF CA friend Llewellyn King were interviewed on Joe Madison – “The Black Eagle” SiriusXM talk show on Urban View Channel 126! Watch it now:  https://www.youtube.com/watch?v=C20MwiYfSGg  In the interview, Linda and Llewellyn discuss the devastating impact of ME/CFS and the urgent need for increased […]

An Exciting Week for Advancing ME/CFS Research  

I’m pleased to share with the OMF Canada community that the OMF-sponsored Stanford ME/CFS Working Group and Third Annual Community Symposium on the Molecular Basis of ME/CFS once again is helping to advance urgently needed research on this disease. During the three days prior to the Community Symposium, 60 scientists from all over the world, […]

Dr. Ron Davis Talks with Llewellyn King about ME/CFS Research

Llewellyn King, host of ME/CFS Alert, has just released his newest episode interviewing OMF Scientific Advisory Board Director Ronald W. Davis, PhD. This edition focuses on the critical research led by Dr. Davis to identify a biomarker for ME/CFS. This is the first in a series of interviews that were recorded at the OMF-sponsored 3rd […]

NEW GUIDELINES FOR DIAGNOSING AND TREATING ME/CFS

A resource for clinicians and patients. The U.S. ME/CFS Clinician Coalition, a group of U.S. ME/CFS experts, has authored a handout on the basics of diagnosis and management of ME/CFS. This handout is being made available on our website for the medical community to help them better understand how to recognize ME/CFS and how to […]

INTRODUCING OPEN MEDICINE FOUNDATION CANADA

WE ARE HERE. Open Medicine Foundation is growing our efforts to bring desperately needed resources and world-class research to the fight against ME/CFS! Please join us as we expand our outreach, advocacy and fundraising across Canada in support of groundbreaking research to end ME/CFS and related chronic complex diseases. Open Medicine Foundation Canada (OMF Canada) […]

Canada invests $1.4M in Biomedical Research

Government of Canada invests $1.4M in biomedical research to improve the quality of life of people living with myalgic encephalomyelitis From: Canadian Institutes of Health Research News release August 22, 2019 – Montréal, Québec – Canadian Institutes of Health Research It is estimated that more than 580,000 Canadians live with myalgic encephalomyelitis (ME), formerly known as […]

The IDO Metabolic Trap Hypothesis for the Etiology of ME/CFS by Robert D. Phair, PhD and Ron Davis, PhD, Stanford Collaboration

By Christopher Armstrong, PhD Dr. Robert Phair has recently published a paper detailing his “metabolic trap” hypothesis underlying ME/CFS, a theory that combines engineering and physiology put together by a man adept in both fields. Dr. Phair is co-founder and Chief Science Officer of Integrative Bioinformatics, Inc, a small company built around a unique software […]

Red Blood Cell Deformability is diminished in patients with Chronic Fatigue Syndrome, by Anand Ramasubramanian, PhD and Ronald Davis, PhD, Stanford Collaboration

As promised, below is the link to the complete version of the Red Blood Cell (RBC) Deformability research paper, which has now been formally published, open source, in Clinical Hemorheology and Microcirculation. The authors are Mohsen Nemat-Gorgani, PhD, of Stanford University, and Anand Ramasubramanian, PhD, of San Jose State University, in collaboration with Ron Davis, PhD, and their teams. This important […]

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Microvesicles and viral sequencing
Microvesicles are a type of extracellular vesicle that is released from the cell membrane. Vesicles are small, fluid-filled sacs or vacuoles within the body. Sequencing is a technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA (or viral) molecule.
NMR Metabolomics
NMR (Nuclear Magnetic Resonance) is an instrument/tool used to perform metabolic studies, metabolic profiling, and metabolomics in biofluids and tissues for more than 40 years using magnetic fields. There is a very close connection between metabolic measurements and NMR. This connection has flourished because of NMR’s many unique strengths for characterizing complex mixtures’ chemical composition.
Proteomics
The large-scale study of proteins, which are large, complex molecules that are required for structure, function, and regulation of the human body's tissues and organs.
Autoantibodies
Antibodies that react with self-molecules and that occur in healthy individuals and are referred to as natural antibodies or autoantibodies.
Extracellular DNA for viral reactivation and Mitochondrial DNA
exDNA (extracellular DNA), exDNA is often secreted actively and is used to perform several tasks, thereby offering an attractive target or tool for biotechnological, medical, environmental, and general microbiological applications. Viruses are intracellular parasites that rely to a significant extent on the host cell for replication. Viral reactivation occurs when an active replication of the viral genome results in a lytic (degradation of the cell) infection characterized by the release of new progeny (descendant) virus particles.
Immune cell profiling
The immune system has many important regulatory roles in disease development and progression. Given the emergence of effective immune therapies, reliable predictors of response are needed. Immune cell profiling determines response by evaluating immune cell populations from treated and untreated samples. For our purposes, we will evaluate the white blood cell response to the viral infection using a process called “Cytof.”
Leukocyte Genomics
A leukocyte is a colorless cell circulating in the blood and body fluids and is involved in counteracting foreign substances and disease. A genome is all genetic material of an organism. Genomics is a biology field focusing on the structure, function, evolution, mapping, and editing of genomes. Therefore, leukocyte genomics is the study of all genetic material of leukocytes.
Metabolomics
Metabolomics is a way to study metabolism – that is, through measuring amounts of the metabolites (small molecules) produced by our bodies as we convert food into energy and other molecules that our cells need to survive. Metabolomics technology is ‘large-scale,’ meaning that several thousand metabolites can be measured from a single sample of e.g., blood or urine.
Micro RNA
Cells use Micro RNA to control whether a particular gene is making too much, too little or the normal amount of its protein at a particular time.