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Category: News

Watch Now: NIH ME/CFS Research Roadmap Webinar Series Recordings!

Overview of webinar topics and images of David Systrom presenting and Linda Tannenbaum networking at the Open Medicine Foundation table.

The ME/CFS Research Roadmap webinars, hosted by the National Institute of Health (NIH), have successfully concluded. These virtual events brought together ME/CFS experts to present current research, identify knowledge gaps, and explore future research opportunities for ME/CFS.    Open Medicine Foundation proudly participated in these webinars, with our team members not only contributing as presenters […]

February 6: New Publication from Jonas Bergquist, MD, PhD, & Colleagues!

Dr. Jonas Bergquist is pictured in his laboratory, wearing a lab coat. Below the image, the title of the publication is displayed.

We are excited to share a new publication from the research funded by Open Medicine Foundation (OMF). Jonas Bergquist, MD, PhD, OMF Chief Medical Officer and Director of the OMF-supported ME/CFS Collaborative Research Center at Uppsala University, and colleagues, have published a study: ‘Analysis of tryptophan metabolites and related compounds in human and murine tissue: development […]

Looking Back and Looking Forward: OMFCA’s 2023 Year in Review!

2023 Year in Review: hands of diverse skin tones connecting pieces of a wooden jigsaw puzzle.

As 2024 begins, we at Open Medicine Foundation Canada are thrilled to review a few highlights and the milestones you made possible in 2023. It was a year filled with incredible achievements, groundbreaking research, and community empowerment.  Thanks to your unwavering support, we’ve reached new heights in our quest to understand and treat ME/CFS, Long COVID and related diseases. We’d […]

New Publication from Alain Moreau, PhD, & Colleagues!

Alan Moreau and exploring the neurocognitive consequences of post-exertional malaise in myalgic encephalomyelitis

Open Medicine Foundation Canada (OMFCA) is thrilled to share a new publication from Alain Moreau, PhD & colleagues: “Exploring the neurocognitive consequences of post-exertional malaise in myalgic encephalomyelitis.” This study shows the impact of post-exertional malaise (PEM) on the disturbance of cognition in the context of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), as well as the […]

Exclusive Interview with Ron Davis & Janet Dafoe!

Ron Davis and Janet Dafoe engaged in a conversation.

We’re thrilled to bring you the latest insights into ME/CFS research through an exclusive interview led by advocate and caregiver Janet Dafoe, Ph.D. Today, Ron Davis, Ph.D., OMF Scientific Advisory Board Director, sits down to discuss his most recent publication: “Catalytic Antibodies May Contribute to Demyelination in Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome.” Access the full publication here.    Immerse yourself in the […]

Just Published: New Publication from Christopher Armstrong and Colleagues!

Chris Armstrong smiling.

Open Medicine Foundation Canada (OMFCA) is proud to share details of a new OMFCA-funded publication from Christopher Armstrong, Ph.D., and colleagues: “In vitro B cell experiments explore the role of CD24, CD38 and energy metabolism in ME/CFS.” Read now!     From the Desk of Dr. Armstrong, Director of the OMF Supported Melbourne ME/CFS Collaboration:  […]

24 hours left! Support OMF before the year ends

Linda Tannenbaum, OMF's Founder and CEO, with a "play video" button.

Thank you for being a supporter of Open Medicine Foundation Canada! 2023 is in thefinal hours. Will you consider making a gift? Make your donation beforethe year ends and help us get further, faster. Donate now This holiday season, we want to remind you that  every research breakthrough … every question explored …  every patient’s story heard …  and every contribution made …  brings us one […]

Time is running out! Make a difference before 2023 ends!

Picture of Agy with a note that says: "Missing from weight lifting, cycling, climbing, trekking, socializing, having friends, walking. Missed out on a career in biomedical science. Missing from life since 2017."

Time is running out! Make a difference before 2023 ends! Your donation to Open Medicine Foundation can help accelerate groundbreaking clinical trials for ME/CFS and Long COVID. Together, we can discover effective treatments faster. Act now to be a part of this vital mission. Your gift gets us further, faster. Donate now As the year […]

Act Now: Your Year-End Donation Matters

An infographic chart shows OMF's 2023 milestones, including 36 active research projects, clinical trials, and the launch of OMF's StudyME Registry.

Imagine a future where both ME/CFS and Long COVID are no longer debilitating conditions. Imagine the challenges in understanding, diagnosing, and finding effective treatments are a thing of the past. At Open Medicine Foundation Canada (OMFCA), we’re committed to turning that future into a reality.  Thanks to the unwavering support of our community, we’ve made significant strides. We […]

Happy Holidays + 7 Holiday Tips for Coping with Chronic Illness!

A pine cone and holly on a snow covered tree branch with the text, "Happy Holidays from your OMF family!"

  As the year draws to a close, we want to take a moment to reflect on the progress we’ve made together and express our heartfelt gratitude to each and every one of you. Your support, whether through donations, fundraising, or sharing our mission, has been invaluable in our quest to understand and conquer ME/CFS […]

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Microvesicles and viral sequencing
Microvesicles are a type of extracellular vesicle that is released from the cell membrane. Vesicles are small, fluid-filled sacs or vacuoles within the body. Sequencing is a technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA (or viral) molecule.
NMR Metabolomics
NMR (Nuclear Magnetic Resonance) is an instrument/tool used to perform metabolic studies, metabolic profiling, and metabolomics in biofluids and tissues for more than 40 years using magnetic fields. There is a very close connection between metabolic measurements and NMR. This connection has flourished because of NMR’s many unique strengths for characterizing complex mixtures’ chemical composition.
Proteomics
The large-scale study of proteins, which are large, complex molecules that are required for structure, function, and regulation of the human body's tissues and organs.
Autoantibodies
Antibodies that react with self-molecules and that occur in healthy individuals and are referred to as natural antibodies or autoantibodies.
Extracellular DNA for viral reactivation and Mitochondrial DNA
exDNA (extracellular DNA), exDNA is often secreted actively and is used to perform several tasks, thereby offering an attractive target or tool for biotechnological, medical, environmental, and general microbiological applications. Viruses are intracellular parasites that rely to a significant extent on the host cell for replication. Viral reactivation occurs when an active replication of the viral genome results in a lytic (degradation of the cell) infection characterized by the release of new progeny (descendant) virus particles.
Immune cell profiling
The immune system has many important regulatory roles in disease development and progression. Given the emergence of effective immune therapies, reliable predictors of response are needed. Immune cell profiling determines response by evaluating immune cell populations from treated and untreated samples. For our purposes, we will evaluate the white blood cell response to the viral infection using a process called “Cytof.”
Leukocyte Genomics
A leukocyte is a colorless cell circulating in the blood and body fluids and is involved in counteracting foreign substances and disease. A genome is all genetic material of an organism. Genomics is a biology field focusing on the structure, function, evolution, mapping, and editing of genomes. Therefore, leukocyte genomics is the study of all genetic material of leukocytes.
Metabolomics
Metabolomics is a way to study metabolism – that is, through measuring amounts of the metabolites (small molecules) produced by our bodies as we convert food into energy and other molecules that our cells need to survive. Metabolomics technology is ‘large-scale,’ meaning that several thousand metabolites can be measured from a single sample of e.g., blood or urine.
Micro RNA
Cells use Micro RNA to control whether a particular gene is making too much, too little or the normal amount of its protein at a particular time.