Driving research of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS),
Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia and Post COVID .


The End ME/CFS Project encompasses OMF funded and facilitated research conducted within five ME/CFS Collaborative Research Centers (CRCs). OMFCA’s guiding strategy focuses on open, collaborative research so that precise diagnostic tools and life-changing treatments can be available to people with related chronic complex diseases as soon as possible.

Funding an internationally-based research network instead of single researchers ensures the stability and collaboration essential for an outcomes-focused, transparent, and multi-pronged approach to finding answers


The five CRCs are working collaboratively to build a repository of data about ME/CFS and related chronic, complex diseases such as Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia and Post COVID-19.

This data is essential to develop diagnostic technologies, understand the molecular basis of the diseases, and uncover effective diagnostic tools and treatments.

ME / CFS Collaborative
Research Center

at Stanford

The Harvard
ME / CFS Collaboration

at Harvard Affiliated Hospitals

ME / CFS Collaborative
Research Center

at Uppsala, Sweden
Major Research Initiatives

With oversight from OMF’s Boards of Directors and Scientific Advisory Board, the following research projects further OMFCA’s Strategic Goals to improve the diagnosis and treatment of ME/CFS, Post-treatment Lyme Disease, and related chronic, complex diseases. 

Post COVID-19 to ME/CFS Research Plan

The current COVID-19 pandemic offers an unprecedented opportunity to understand how a viral infection may convert to ME/CFS in some patients.

The five ME/CFS Collaborative Centers have begun a unique,  extensive, in-depth longitudinal molecular study following COVID-19 patients. Their shared goal is to determine the pathways involved in maintaining long-term symptoms in some patients,  possibly converting to ME/CFS. They seek to learn about these pathways so as to develop biomarkers, novel drug targets,  new treatment, and prevention strategies.

OMF–Funded Research Publications
Help us accelerate this urgent research!