Driving research of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS),
Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia and Post COVID .

The ME/CFS Collaboration
at Uppsala University

State-of-the-art laboratory searching for biomarkers of
Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS) in body and brain

Core Aims

What we hope to achieve


Our fundamental philosophy

Science Team

List of scientific collaborators


Current research projects

About the research centER

Established in 2019, this research center is directed by Jonas Bergquist, MD, PhD. Prior to this new center, Dr. Bergquist had already been researching ME/CFS for nearly a decade. Dr. Bergquist and his lab develop novel methods for extracting patient samples and measuring the metabolites and proteins within those samples. They then apply these methods to produce unique and valuable data from a range of diseases.  Along with ME/CFS, his lab has a general interest in neurodegenerative diseases such as Parkinson’s, Alzheimer’s, amyotrophic lateral sclerosis (ALS) and multiple sclerosis (MS). 

The ME/CFS CRC at Uppsala University is looking for ME/CFS biomarkers to develop a diagnostic test and to contribute to the understanding of what initiates the disease process.  Not only are they looking for single metabolites or proteins, they are looking for the pattern of all the data the extract from ME/CFS patient samples and are working towards a defining biochemical signature of the disease.

This collaborative research initiative is looking to develop methods to measure proteins, peptides and metabolites in the blood and cerebrospinal fluid of ME/CFS patients to help define the underlying biological cause, to form a diagnostic and to ultimately find treatments for the disease. 

Core Aims

Fundamental Philosophy

Current Studies


Autoimmunity and Autoantibodies

Autoimmunity and Autoantibodies in ME/CFS STUDY AIM Investigate potential differences in adrenergic and muscarinic receptor autoantibody levels in plasma and cerebrospinal fluid (CSF) samples between …

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Post-viral Encephalopathy

Herpes Simplex Encephalopathy and the Development of ME / CFS STUDY AIM To investigate the correlation between biomarkers for brain injury and long-term neurocognitive outcome, and the …

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Kynurenine Trial in ME/CFS

Kynurenine Trial in ME/CFS STUDY AIM The purpose of the study is to evaluate whether kynurenine is directly connected to ME/CFS patient symptom severity. LEAD …

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Scientific Team

The large-scale research endeavors of the ME / CFS Collaborative Research Center at Uppsala University require a diverse team. Dr. Bergquist has assembled a great team of scientists and clinicians to fulfill their goals.

Uppsala University (Sweden)

Jonas Bergquist, MD, PhD, Prof, Director

Kumari Ubhayasekhera, PhD

Sandy Abujrais. PhD Student

Annie Bynke, Med Student

Torsten Gordh, MD, PhD, Prof em


Massachusetts General Hospital (Harvard)

Ronald Tompkins, MD, ScD

Wenzhong Xiao, PhD


Stanford University

Ronald Davis, PhD


Karolinska Institut (Sweden)

Per Julin, MD, PhD

Anders Rehnström, MD

Anna Lindquist, MD

Emelie Karlsson, RN

Bragee Clinics Stockholm

Bo C. Bertilsson, MD, PhD

Björn Bragée, MD

Gunnar Olsson, MD, PhD, Ass. Prof

Jonas Axelsson, MD, PhD, Ass. Prof

Britt Bragée, RPT, PhD

Gabriella Bernhoff RPT, PhD Student

Brandon Drum, Med Student

Michael Fahlqvist, MD-internship

Michos Anastasios, MD


Gottfries clinic (Sweden)

CG Gottfries, MD, PhD, Prof em

Linkoping University (Sweden)

Anders Rosén, MD, PhD, Prof em

Björn Ingelsson,  PhD, Ass prof

Eirini Apostoulo, PhD, Post doc

Rizwan Muhammad, Guest Researcher


University of East Anglia (UK)

Simon Carding, PhD, Prof


Charite Universitatsmedizin Berlin

Carmen Scheibenbogen, MD, PhD, Prof


Open Medicine Foundation

Linda Tannenbaum

Chris Armstrong, PhD

Learn about Our Other OMF Funded Collaborative Research Centres